Strain Report - Rat Genome Database

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Strain: SD-Nfe2l2em1Mcwi

Symbol: SD-Nfe2l2em1Mcwi
Strain: SD-Nfe2l2em1
Substrain: Mcwi
RGD ID: 9588552
Citation ID: RRID:RGD_9588552
Ontology ID: RS:0003831
Alleles: Nfe2l2em1Mcwi
Also Known As: SD-Nfe2l2em1Mcwi; SD-Nfe2l2^[em1Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting TALENs targeting the sequence TAGTCCTGGCGGTGGCAATTCCAAGTCCATCATGCTGAGGGCGGACGCTGCGCTA into Crl:SD Sprague Dawley rat embryos. The resulting mutation is a 41-bp deletion in exon 1.
Last Known Status: Live Animals (as of 2017-01-26)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2360,621,570 - 60,621,610RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0362,524,893 - 62,524,933RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0369,041,641 - 69,069,190RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4358,366,693 - 58,394,116RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Nfe2l2em1Mcwi-var1 chr3 60621570 60621610 TGTAGTCCTGGCGGTGGCAATTCCAAGTCCATCATGCTGAG - deletion mRatBN7.2
Nfe2l2em1Mcwi-var1 chr3 62524893 62524933 TGTAGTCCTGGCGGTGGCAATTCCAAGTCCATCATGCTGAG - deletion Rnor_6.0

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-24 SD-Nfe2l2em1Mcwi    SD-Nfe2l2em1Mcwi    Name updated 68913 APPROVED
2015-04-24 SD-Nfe2l2em1Mcwi    SD-Nfe2l2em1Mcwi    Name updated 68913 APPROVED