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Strain Registration

Strain: DA.PVG.1AV1-(D13Rat105-D13Rat131)/Kini

Symbol: DA.PVG.1AV1-(D13Rat105-D13Rat131)/Kini
Strain: DA.PVG.1AV1-(D13Rat105-D13Rat131)
Substrain: Kini
RGD ID: 8552348
Citation ID: RRID:RGD_8552348
Ontology ID: RS:0003749
Also Known As: DA.PVG.1AV1-(D13Rat105-D13Rat131)/Kini; DA.PVG.1AV1-Eae34; NBRP Rat No: 0702
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: Center for Molecular Medicine, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
Description: Inbred Dark Agouti (DA) rats were originally obtained from Hannover, Germany and Piebald Virol Glaxo(PVG) rats from Harlan UK Limited (Blackthorn, UK). The congenic line was established from DA and MHC-identical PVG.A rats using a speed-congenic approach with marker assisted selection. DA females were mated with male offspring selected from F2 (DAxPVG.A) with heterozygote alleles within chromosome 13 and Eae34 QTL interval and with the lowest PVG.A background contamination using 96 microsatellite markers equally spaced throughout the genome (at 20 centimorgan cM intervals). A breeding pair selected from the N7 generation were crossed for two generations to produce homozygous DA.PVG-Eae34 congenic rats.
Coat Color: agouti
Last Known Status: Cryopreserved Sperm
Research Usage Neurobiology
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21344,139,595 - 77,313,088RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01349,478,067 - 83,263,907RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01354,552,997 - 88,144,258RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41345,592,985 - 80,755,583RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D13Rat105)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21344,139,595 - 44,139,796 (+)MAPPER
Rnor_6.01349,478,067 - 49,478,267NCBI
Rnor_5.01354,552,997 - 54,553,197UniSTS
RGSC_v3.41345,592,985 - 45,593,186RGD
RGSC_v3.41345,592,986 - 45,593,186UniSTS
RGSC_v3.11345,607,028 - 45,607,229RGD
Celera1344,473,240 - 44,473,440UniSTS
FHH x ACI Map1318.27RGD
FHH x ACI Map1318.27UniSTS
Cytogenetic Map13q13UniSTS

Flank 2 / 1 (D13Rat131)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21377,312,933 - 77,313,088 (+)MAPPER
Rnor_6.01383,263,753 - 83,263,907NCBI
Rnor_5.01388,144,104 - 88,144,258UniSTS
RGSC_v3.41380,755,428 - 80,755,583RGD
RGSC_v3.41380,755,429 - 80,755,583UniSTS
RGSC_v3.11380,769,617 - 80,769,771RGD
Celera1377,028,944 - 77,029,098UniSTS
RH 3.4 Map13491.0UniSTS
RH 3.4 Map13491.0RGD
SHRSP x BN Map1333.9798UniSTS
SHRSP x BN Map1333.9798RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Partial exacerbation of experimental autoimmune encephalomyelitis (EAE) compared to the susceptible parental DA strain. 1302502
strain_reproduction Good breeding performance 1302502