Strain Report - Rat Genome Database

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Strain: SS.LEW-(D18Rat55-D18Mgh2)/Ayd

Symbol: SS.LEW-(D18Rat55-D18Mgh2)/Ayd
Strain: SS.LEW-(D18Rat55-D18Mgh2)
Substrain: Ayd
RGD ID: 8551787
Citation ID: RRID:RGD_8551787
Ontology ID: RS:0003680
Previously known as: SS.Lewis-(D18Chm124-D18Rat61)/Lt; SS.LEW-(D18Chm124-D18Rat61)/Ayd; SS.LEW-(D18Chm124-D18Rat61)/Ayd; SS.LEW-(D18Rat55-D18Mgh2)/Ayd; C18S.L14
Type: congenic
Source: Research Centre-CHUM, Montreal, Quebec, Canada
Origin: SS/Jr and LEW/Crlc were backcrossed for 5 generations, then BC5 rat was mated with LEW/Crlc to produce the desired congenic strain
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21852,539,763 - 59,712,417RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01854,108,375 - 61,901,354RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01853,346,348 - 61,092,546RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41854,856,551 - 62,313,296RGD_MAPPER_PIPELINERGSC3.4

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table

Clinical Measurement
mean arterial blood pressure


References - curated
# Reference Title Reference Citation
1. Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci. Chauvet C, etal., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.
2. alpha-Kinase 2 is a novel candidate gene for inherited hypertension in Dahl rats. Chauvet C, etal., J Hypertens. 2011 Jul;29(7):1320-6. doi: 10.1097/HJH.0b013e32834705e4.
3. Combining distinctive and novel loci doubles BP reduction, reverses diastolic dysfunction and mitigates LV hypertrophy. Crespo K, etal., J Hypertens. 2013 May;31(5):927-35. doi: 10.1097/HJH.0b013e32835edc7e.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Position Markers

Flank 1 / 1 (D18Rat55)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21852,539,763 - 52,539,863 (+)MAPPER
Rnor_6.01854,108,375 - 54,108,474NCBI
Rnor_5.01853,346,348 - 53,346,447UniSTS
RGSC_v3.41854,856,552 - 54,856,651UniSTS
RGSC_v3.41854,856,551 - 54,856,651RGD
RGSC_v3.11854,928,784 - 54,928,883RGD
Celera1850,643,852 - 50,643,951UniSTS
RH 3.4 Map18497.9RGD
RH 3.4 Map18497.9UniSTS
RH 2.0 Map18411.9RGD
SHRSP x BN Map1822.7899RGD
FHH x ACI Map1831.46RGD
Cytogenetic Map18q12.1UniSTS

Flank 2 / 1 (D18Mgh2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21859,712,234 - 59,712,417 (+)MAPPER
Rnor_6.01861,901,172 - 61,901,354NCBI
Rnor_5.01861,092,364 - 61,092,546UniSTS
RGSC_v3.41862,313,112 - 62,313,296RGD
RGSC_v3.41862,313,114 - 62,313,296UniSTS
RGSC_v3.11862,386,313 - 62,386,497RGD
Celera1857,832,923 - 57,833,105UniSTS
RH 3.4 Map18602.5UniSTS
RH 3.4 Map18602.5RGD
RH 2.0 Map18310.1RGD
Cytogenetic Map18q12.1UniSTS

Additional Information