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Strain Registration

Strain: SS.MNS-(D2Chm161-D2Chm410)/Ayd

Symbol: SS.MNS-(D2Chm161-D2Chm410)/Ayd
Strain: SS.MNS-(D2Chm161-D2Chm410)
Substrain: Ayd
RGD ID: 7421647
Citation ID: RRID:RGD_7421647
Ontology ID: RS:0003594
Also Known As: SS.MNS-(D2Chm161-D2Chm408)/Ayd; SS.MNS-(D2Chm161-D2Chm408)/Ayd; C2S.M21; DSS.MNS-(D2Chm161-D2Chm410)/Lt; DSS.MNS-(D2Chm161-D2Mgh10)/Lt; SS.MNS-(D2Chm161-D2Chm410)/Ayd
Type: congenic
Available Source: Not Available
Origination: Centre Hospitalier de Universite de Montreal (CRCHUM), Quebec, Canada
Description: Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous rat was then backcrossed to SS/Jr rat to duplicate the fragment.
Last Known Status: Unknown





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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Clinical Measurement
mean arterial blood pressure

References

References - curated
# Reference Title Reference Citation
1. Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci. Chauvet C, etal., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.
2. Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis. Chauvet C, etal., Hypertens Res. 2009 Jul;32(7):631-7. doi: 10.1038/hr.2009.70. Epub 2009 May 22.
3. Genetics of systolic and diastolic heart failure. Deng AY J Hypertens. 2015 Jan;33(1):3-13. doi: 10.1097/HJH.0000000000000400.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Bp365 Blood pressure QTL 365 arterial blood pressure trait   (VT:2000000)    

Additional Information