Strain Report - Rat Genome Database

Name: SS.MNS-( D2Rat155-D2Chm419 )/Ayd
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: SS.MNS-(D2Rat155-D2Chm419)/Ayd

Symbol:

SS.MNS-(D2Rat155-D2Chm419)/Ayd

Strain:

SS.MNS-(D2Rat155-D2Chm419)

Substrain:

Ayd

RGD ID:

7421645

Citation ID:

RRID:RGD_7421645

Ontology ID:

RS:0003593

Previously known as:

C2S.M19; DSS.MNS-(D2Rat155-D2Chm419)/Lt; SS.MNS-(D2Rat155-D2Chm419)/Ayd

Type:

congenic

Source:

Centre Hospitalier de Universite de Montreal (CRCHUM), Quebec, Canada

Origin:

Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F₂ rats were genotyped with markers that resided in the region of interest, heterozygous rat was then backcrossed to SS/Jr rat to duplicate the fragment.

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	172,982,062 - 172,982,266	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	2	186,889,035 - 186,889,238	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	2	206,293,779 - 206,293,982	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	2	179,581,946 - 179,582,150	RGD_MAPPER_PIPELINE	RGSC3.4

Congenic Strains

SS.MNS-(D2Rat155-D2Chm419),LEW-(D10Chm10-D10Rat11)/Ayd

SS.MNS-(D2Rat155-D2Chm419),LEW-(D10Rat194-D10Chm243)/Ayd

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hypotension (IAGP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased systemic arterial blood pressure (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

Options:

View chart

Download data table

View expanded data table

Clinical Measurement

mean arterial blood pressure

References

References - curated

#	Reference Title	Reference Citation
1.	Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci.	Chauvet C, etal., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.
2.	Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis.	Chauvet C, etal., Hypertens Res. 2009 Jul;32(7):631-7. doi: 10.1038/hr.2009.70. Epub 2009 May 22.
3.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D2Rat155)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	172,982,062 - 172,982,266 (+)	MAPPER
Rnor_6.0	2	186,889,035 - 186,889,238	NCBI
Rnor_5.0	2	206,293,779 - 206,293,982	UniSTS
RGSC_v3.4	2	179,581,946 - 179,582,150	RGD
RGSC_v3.4	2	179,581,947 - 179,582,150	UniSTS
RGSC_v3.1	2	179,532,053 - 179,532,256	RGD
Celera	2	166,933,605 - 166,933,808	UniSTS
RH 3.4 Map	2	1138.1	RGD
RH 3.4 Map	2	1138.1	UniSTS
SHRSP x BN Map	2	70.0898	UniSTS
SHRSP x BN Map	2	70.0898	RGD
FHH x ACI Map	2	76.5599	RGD
Cytogenetic Map	2	q34	UniSTS

Strain QTL Data

Symbol	Name	Trait
Bp363	Blood pressure QTL 363	arterial blood pressure trait (VT:2000000)

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: SS.MNS-(D2Rat155-D2Chm419)/Ayd

Mammalian Phenotype

Related Phenotype Data for Term "SS.MNS-(D2Rat155-D2Chm419)/Ayd" (RS:0003593)