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Strain Registration

Strain: SS.LEW-(D17Chm131-D17Chm93)/Ayd

Symbol: SS.LEW-(D17Chm131-D17Chm93)/Ayd
Strain: SS.LEW-(D17Chm131-D17Chm93)
Substrain: Ayd
RGD ID: 7421621
Citation ID: RRID:RGD_7421621
Ontology ID: RS:0003586
Previously known as: C17S.L11; SS.LEW-(D17Chm31-D17Chm93)/Ayd; SS.LEW-(D17Chm131-D17Chm71)/Ayd; SS.LEW-(D17Chm131-D17Chm93)/Ayd
Type: congenic
Source: Centre Hospitalier de Universite de Montreal (CRCHUM), Quebec, Canada
Origin: A segment of chromosome 17 was transferred from LEW/Crlc into the SS/Jr background, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous rat was then backcrossed to SS/Jr rat to duplicate the fragment.
Last Known Status: Unknown





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table

Clinical Measurement
mean arterial blood pressure

References

References - curated
# Reference Title Reference Citation
1. Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci. Chauvet C, etal., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.
2. Combining distinctive and novel loci doubles BP reduction, reverses diastolic dysfunction and mitigates LV hypertrophy. Crespo K, etal., J Hypertens. 2013 May;31(5):927-35. doi: 10.1097/HJH.0b013e32835edc7e.
3. Genetics of systolic and diastolic heart failure. Deng AY J Hypertens. 2015 Jan;33(1):3-13. doi: 10.1097/HJH.0000000000000400.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Bp369 Blood pressure QTL 369 arterial blood pressure trait   (VT:2000000)    

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-11 SS.LEW-(D17Chm131-D17Chm93)/Ayd    SS.LEW-(D17Chm31-D17Chm93)/Ayd    Symbol and/or name change 68913 APPROVED