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Strain: DA.PVG.1AV1-(D4Mgh17-D4Rat56)

Symbol: DA.PVG.1AV1-(D4Mgh17-D4Rat56)
Strain: DA.PVG.1AV1-(D4Mgh17-D4Rat56)
RGD ID: 737859
Citation ID: RRID:RGD_737859
Ontology ID: RS:0000226
Also known as: DA.C4R2[PVG]; DA.PVG.1AV1 chromosome 4 R2subcongenic; DA.PVG.1AV1-(D4Mgh17-D4Rat56)
Type: congenic
Source: Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
Origin: Congenic substrain derived from marker assisted selection for PVG.1AV1 chromsome 4 alleles on the DA recipient strain.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24114,921,280 - 114,921,417RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.04113,100,978 - 113,247,809RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04177,782,842 - 204,673,386RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.44116,611,031 - 143,663,540RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
1. Backdahl L, etal., Arthritis Rheum 2003 Feb;48(2):551-9.
2. RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D4Mgh17)
Rat AssemblyChrPosition (strand)Source
mRatBN7.24114,921,280 - 114,921,417 (+)MAPPER
Rnor_6.04113,100,978 - 113,101,114NCBI
Rnor_6.04113,247,673 - 113,247,809NCBI
Rnor_5.04177,782,842 - 177,782,978UniSTS
Rnor_5.04177,926,531 - 177,926,667UniSTS
RGSC_v3.44116,611,031 - 116,611,168RGD
RGSC_v3.44116,611,032 - 116,611,168UniSTS
RGSC_v3.14116,855,512 - 116,855,649RGD
Celera4103,918,469 - 103,918,605UniSTS
RH 3.4 Map4660.47RGD
RH 3.4 Map4660.47UniSTS
RH 2.0 Map4668.7RGD
Cytogenetic Map4q34UniSTS

Flank 2 / 1 (D4Rat56)
Rat AssemblyChrPosition (strand)Source
Rnor_5.04204,672,972 - 204,673,386NCBI
RGSC_v3.44143,663,127 - 143,663,540RGD
RGSC_v3.14143,907,968 - 143,908,381RGD
RH 3.4 Map4881.0RGD
RH 3.4 Map4881.0UniSTS
RH 2.0 Map4904.3RGD
SHRSP x BN Map463.48RGD
FHH x ACI Map484.64RGD
Strain QTL Data
Symbol Name Trait
Pia9 Pristane induced arthritis QTL 9 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics QTLs Cia3, Aia3, and Pia5 are contained within subcongenic strain DA.PVG.1AV1-(D4Mgh17-D4Rat56). 629560
strain_drgs_chems These animals have reduced susceptibility to experimentally induced arthritis (induced by collagen, pristane, squalene and other adjuvants) compared to the DA recipient strain having no PVG chromosome 4 alleles. 629560
strain_life_disease Males have reduced susceptibility to experimentally induced arthritis compared to the DA recipient strain having no PVG chromosome 4 alleles. 629560
strain_life_disease Males show down-regulation of accumalated arthiris severity over time. 629560

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-27 DA.PVG.1AV1-(D4Mgh17-D4Rat56   DA.PVG.1AV1-(D4Mgh17-D4Rat56   Name updated 68913 APPROVED
2013-08-27 DA.PVG.1AV1-(D4Mgh17-D4Rat56   DA.PVG.1AV1-(D4Mgh17-D4Rat56   Name updated 68913 APPROVED