Strain Report - Rat Genome Database

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Strain: DA.PVG.1AV1-(D4Rat155-D4Rat84)

Symbol: DA.PVG.1AV1-(D4Rat155-D4Rat84)
Strain: DA.PVG.1AV1-(D4Rat155-D4Rat84)
RGD ID: 737857
Citation ID: RRID:RGD_737857
Ontology ID: RS:0000227
Previously known as: DA.C4[PVG]; DA.PVG.1AV1 chromosome 4 congenic; DA.PVG.1AV1-(D4Rat155-D4Rat84)
Type: congenic
Source: Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
Origin: Congenic strain derived from marker assisted selection for PVG.1AV1 chromsome 4 alleles on the DA recipient strain.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2449,524,674 - 180,699,135RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0448,053,950 - 182,171,018RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0447,848,402 - 246,313,537RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.44185,398,415 - 185,398,530RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
1. Backdahl L, etal., Arthritis Rheum 2003 Feb;48(2):551-9.
2. RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D4Rat155)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2449,524,674 - 49,524,880 (+)MAPPER
Rnor_6.0448,053,950 - 48,054,155NCBI
Rnor_5.0447,848,402 - 47,848,607UniSTS
Celera444,734,838 - 44,735,043UniSTS
RH 3.4 Map4300.42UniSTS
RH 3.4 Map4300.42RGD
RH 2.0 Map4355.3RGD
SHRSP x BN Map429.49RGD

Flank 2 / 1 (D4Rat84)
Rat AssemblyChrPosition (strand)Source
mRatBN7.24180,699,020 - 180,699,135 (+)MAPPER
Rnor_6.04182,170,904 - 182,171,018NCBI
Rnor_5.04246,313,423 - 246,313,537UniSTS
RGSC_v3.44185,398,416 - 185,398,530UniSTS
RGSC_v3.44185,398,415 - 185,398,530RGD
RGSC_v3.14185,643,540 - 185,643,654RGD
Celera4169,180,864 - 169,180,990UniSTS
RH 3.4 Map41096.4RGD
RH 3.4 Map41096.4UniSTS
SHRSP x BN Map499.9UniSTS
SHRSP x BN Map499.9RGD
FHH x ACI Map4113.49RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics QTLs Aia2, Pia2, Cia3, Aia3, Pia5, Oia2, Cia13, and Pia7 are contained within the PVG chromosome 4 segment within a 70 cM interrval, transferred in this congenic strain. 629560
strain_drgs_chems These have reduced susceptibility to experimentally induced arthritis (induced by collagen, pristane, squalene and other adjuvants) compared to the DA recipient strain having no PVG chromosome 4 alleles. 629560
strain_life_disease These have reduced susceptibility to experimentally induced arthritis compared to the DA recipient strain having no PVG chromosome 4 alleles. 629560
strain_life_disease 107 out of 109 rats develpoed symmetric polyarthiritis. 629560