Strain Report - Rat Genome Database

Name: DA.PVG.1AV1-( D4Rat155-D4Rat84 )
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: DA.PVG.1AV1-(D4Rat155-D4Rat84)

Symbol:

DA.PVG.1AV1-(D4Rat155-D4Rat84)

Strain:

DA.PVG.1AV1-(D4Rat155-D4Rat84)

RGD ID:

737857

Citation ID:

RRID:RGD_737857

Ontology ID:

RS:0000227

Previously known as:

DA.C4[PVG]; DA.PVG.1AV1 chromosome 4 congenic; DA.PVG.1AV1-(D4Rat155-D4Rat84)

Type:

congenic

Source:

Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden

Origin:

Congenic strain derived from marker assisted selection for PVG.1AV1 chromsome 4 alleles on the DA recipient strain.

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	49,524,674 - 180,699,135	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	4	48,053,950 - 182,171,018	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	4	47,848,402 - 246,313,537	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	4	185,398,415 - 185,398,530	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Arthritis (IAGP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

joint inflammation (IAGP)

weight loss (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

Options:

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Download data table

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Clinical Measurement

maximum body weight loss to initial body weight ratio

post-insult time to onset of experimental arthritis

percentage of study population developing experimental arthritis during a period of time

serum orosomucoid 1 level

References

References - curated


1.	Backdahl L, etal., Arthritis Rheum 2003 Feb;48(2):551-9.
2.	RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D4Rat155)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	4	49,524,674 - 49,524,880 (+)	MAPPER
Rnor_6.0	4	48,053,950 - 48,054,155	NCBI
Rnor_5.0	4	47,848,402 - 47,848,607	UniSTS
Celera	4	44,734,838 - 44,735,043	UniSTS
RH 3.4 Map	4	300.42	UniSTS
RH 3.4 Map	4	300.42	RGD
RH 2.0 Map	4	355.3	RGD
SHRSP x BN Map	4	29.49	RGD

Flank 2 / 1 (D4Rat84)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	4	180,699,020 - 180,699,135 (+)	MAPPER
Rnor_6.0	4	182,170,904 - 182,171,018	NCBI
Rnor_5.0	4	246,313,423 - 246,313,537	UniSTS
RGSC_v3.4	4	185,398,416 - 185,398,530	UniSTS
RGSC_v3.4	4	185,398,415 - 185,398,530	RGD
RGSC_v3.1	4	185,643,540 - 185,643,654	RGD
Celera	4	169,180,864 - 169,180,990	UniSTS
RH 3.4 Map	4	1096.4	RGD
RH 3.4 Map	4	1096.4	UniSTS
SHRSP x BN Map	4	99.9	UniSTS
SHRSP x BN Map	4	99.9	RGD
FHH x ACI Map	4	113.49	RGD

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_characteristics	QTLs Aia2, Pia2, Cia3, Aia3, Pia5, Oia2, Cia13, and Pia7 are contained within the PVG chromosome 4 segment within a 70 cM interrval, transferred in this congenic strain.	629560
strain_drgs_chems	These have reduced susceptibility to experimentally induced arthritis (induced by collagen, pristane, squalene and other adjuvants) compared to the DA recipient strain having no PVG chromosome 4 alleles.	629560
strain_life_disease	These have reduced susceptibility to experimentally induced arthritis compared to the DA recipient strain having no PVG chromosome 4 alleles.	629560
strain_life_disease	107 out of 109 rats develpoed symmetric polyarthiritis.	629560

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: DA.PVG.1AV1-(D4Rat155-D4Rat84)

Related Phenotype Data for Term "DA.PVG.1AV1-(D4Rat155-D4Rat84)" (RS:0000227)