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Strain Registration

Strain: SS-Sorcs2em1Mcwi

Symbol: SS-Sorcs2em1Mcwi
Strain: SS-Sorcs2em1
Substrain: Mcwi
RGD ID: 7364882
Citation ID: RRID:RGD_7364882
Ontology ID: RS:0003528
Alleles: Sorcs2em1Mcwi
Also Known As: SS-Sorcs2em1Mcwi; SS-Sorcs2^[em1Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence ATCGTCGCCATCATCATCatcagcGGACTGGTCCTCCTG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 34-bp frameshift deletion in exon 15.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21474,711,197 - 74,711,230RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01479,538,911 - 79,912,333RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01479,176,694 - 79,547,823RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41479,968,072 - 80,344,330RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Sorcs2em1Mcwi-var1 chr14 74711197 74711230 CTGACTGGGAGCTGGTCAAGGTGGACTTCCGGCC - deletion mRatBN7.2

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-03 SS-Sorcs2em1Mcwi    SS-Sorcs2em1Mcwi    Symbol updated 68687 APPROVED
2014-04-03 SS-Sorcs2em1Mcwi    SS-Sorcs2em1Mcwi    Symbol updated 68687 APPROVED
2014-04-03 SS-Sorcs2em1Mcwi    SS-Sorcs2em1Mcwi    Name updated 68913 APPROVED
2014-04-03 SS-Sorcs2em1Mcwi    SS-Sorcs2em1Mcwi    Name updated 68913 APPROVED
2013-10-18 SS-Sorcs2em1Mcwi    SS-Sorcs2em1Mcwi    Name updated 68913 APPROVED
2013-10-18 SS-Sorcs2em1Mcwi    SS-Sorcs2em1Mcwi    Name updated 68913 APPROVED