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Strain Registration

Strain: DA.E3-(D14Wox8-D14Rat64)/Rhd

Symbol: DA.E3-(D14Wox8-D14Rat64)/Rhd
Strain: DA.E3-(D14Wox8-D14Rat64)
Substrain: Rhd
RGD ID: 731195
Citation ID: RRID:RGD_731195
Ontology ID: RS:0000204
Previously known as: DA.Pia6; DA.E3-(D14Wox8-D14Rat64)/Rhd
Type: congenic
Source: Medical Inflammation Research, BMC, University of Lund, Lund, Sweden
Origin: The fragment of interest is transferred from arthritis resistant E3 strain to the susceptible DA strain.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21463,618,971 - 63,619,178RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01467,944,692 - 67,944,898RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01467,969,510 - 67,969,716RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41468,573,958 - 68,574,165RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
arthritis  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. Chronicity of pristane-induced arthritis in rats is controlled by genes on chromosome 14. Wester L, etal., J Autoimmun 2003 Dec;21(4):305-13.

Region

Position Markers

Flank 1 / 1 (D14Wox8)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map14224.4UniSTS
RH 3.4 Map14224.4RGD
RH 2.0 Map14212.6RGD
Cytogenetic Map14p21UniSTS

Flank 2 / 1 (D14Rat64)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21463,618,971 - 63,619,178 (+)MAPPER
Rnor_6.01467,944,692 - 67,944,898NCBI
Rnor_5.01467,969,510 - 67,969,716UniSTS
RGSC_v3.41468,573,959 - 68,574,165UniSTS
RGSC_v3.41468,573,958 - 68,574,165RGD
RGSC_v3.11468,576,350 - 68,576,556RGD
Celera1462,645,114 - 62,645,320UniSTS
RH 3.4 Map14468.2RGD
RH 3.4 Map14468.2UniSTS
RH 2.0 Map14599.3RGD
SHRSP x BN Map1430.53RGD
FHH x ACI Map1445.9899RGD
Cytogenetic Map14q11UniSTS
Strain QTL Data
Symbol Name Trait
Pia20 Pristane induced arthritis QTL 20 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease The transferred 30 cM fragment contains the arthritis QTL Pia6. 730280
strain_life_disease Chronic active phase of arthritis starts 5 weeks after the onset of arthritis. 730280
strain_phys_biochem The concentration of a1-microglobulin increased and the concentration of a1-acid glycoprotein decreased during the disease course. 730280

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-04-14 DA.E3-(D14Wox8-D14Rat64)/Rhd    DA.E3-(D14Wox8-D14Rat64)/Rhd    Data merged 737654 APPROVED