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Strain Registration

Strain: SHRSP.WKY-(Klk1-D1Rat116)/Izm

Symbol: SHRSP.WKY-(Klk1-D1Rat116)/Izm
Strain: SHRSP.WKY-(Klk1-D1Rat116)
Substrain: Izm
RGD ID: 731189
Citation ID: RRID:RGD_731189
Ontology ID: RS:0000772
Previously known as: SHRSP.WKY-(Klk1-D1Rat116)/IzmTkyo; SHRSP.WKY-(Klk1-D1Rat116)/Izm
Type: congenic
Source: Department of Gene Diagnostics and Therapeutics, International Medical Center of Japan, Toyama, Shinjuku-ku, Tokyo, Japan
Origin: A segment of RNO1 (~70 cM in size) was transferred from WKY/Izm onto the genetic background of SHRSP/Izm by the speed congenic method.
Last Known Status: Unknown





References

References - curated
# Reference Title Reference Citation
1. Isolation of a Chromosome 1 Region Affecting Blood Pressure and Vascular Disease Traits in the Stroke-Prone Rat Model. Kato N, etal., Hypertension 2003 Dec;42(6):1191-7. Epub 2003 Nov 17.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Bp154 Blood pressure QTL 154 arterial blood pressure trait   (VT:2000000)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease The systolic blood pressure was lowered by 20-80 mm Hg which exaggerated impaired glucose tolerance and helped in preventing apparent stroke. 730283
strain_life_disease Blood pressure differences were more prominent in males than in females; fasting plasma glucose levels were much higher in females than in males. 730283