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Strain Registration

Strain: F344.BN-(D3Mgh13-D3Mgh7)/Dlw

Symbol: F344.BN-(D3Mgh13-D3Mgh7)/Dlw
Strain: F344.BN-(D3Mgh13-D3Mgh7)
Substrain: Dlw
RGD ID: 728146
Citation ID: RRID:RGD_728146
Ontology ID: RS:0000273
Also Known As: F344.BN-Edpm3; F344/NHsd-Edpm3BN; F344.BN-(D3Mgh13-D3Mgh7)/Dlw
Type: congenic
Available Source: Not Available
Origination: Department of Biological Sciences, Oakland University, Rochester, MI
Description: This congenic strain carries the BN Edpm3 QTL along with many BN chromosome 3 markers on an F344 background. This strain is maintained at Oakland University, Rochester MN, USA
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2310,549,351 - 112,272,465RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.035,775,856 - 117,288,411RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0311,139,240 - 123,812,293RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.43112,319,451 - 112,319,585RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Angiogenesis and capillary maturation phenotypes associated with the Edpm3 locus on rat chromosome 3. Pandey J and Wendell DL, Mamm Genome. 2006 Jan;17(1):49-57. Epub 2006 Jan 13.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. A congenic strain of rat for investigation of control of estrogen-induced growth. Wendell DL, etal., Mamm Genome 2002 Nov;13(11):664-6.

Region

Position Markers

Flank 1 / 1 (D3Mgh13)
Rat AssemblyChrPosition (strand)Source
mRatBN7.23112,272,331 - 112,272,465 (+)MAPPER
Rnor_6.03117,288,278 - 117,288,411NCBI
Rnor_5.03123,812,160 - 123,812,293UniSTS
RGSC_v3.43112,319,451 - 112,319,585RGD
RGSC_v3.43112,319,452 - 112,319,585UniSTS
RGSC_v3.13112,225,024 - 112,225,158RGD
Celera3111,130,622 - 111,130,755UniSTS
SHRSP x BN Map354.0398UniSTS
SHRSP x BN Map354.0398RGD
FHH x ACI Map361.75RGD
Cytogenetic Map3 RGD

Flank 2 / 1 (D3Mgh17)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2310,549,351 - 10,549,499 (+)MAPPER
Rnor_6.035,775,856 - 5,776,005NCBI
Rnor_5.0311,139,240 - 11,139,389UniSTS
Celera35,345,934 - 5,346,083UniSTS
RH 3.4 Map321.9RGD
RH 3.4 Map321.9UniSTS
Cytogenetic Map3p12UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems Displays pituitary tumor growth in response to chronic estrogen stimulation, however, the pituitary tumors are smaller than those observed in the F344 background strain alone 629581
strain_life_disease The presence of a small amount of pituitary tumor growth in this congenic strain is attributed to the effects of other QTLs associated with estrogen dependent pituitary mass growth. 629581
strain_phys_biochem Estrogen-induced tumors are deficient in vessel maturation and have higher tumor vascularity. 1581610