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Options: | View chart | | | Download data table | | | View expanded data table |
# | Reference Title | Reference Citation |
1. | Finerenone Reduces Intrinsic Arterial Stiffness in Munich Wistar Frömter Rats, a Genetic Model of Chronic Kidney Disease. | Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
2. | Glomerular hypertrophy precedes albuminuria and segmental loss of podoplanin in podocytes in Munich-Wistar-Fromter rats. | Ijpelaar DH, etal., Am J Physiol Renal Physiol. 2008 Apr;294(4):F758-67. Epub 2008 Jan 16. |
3. | RGD Strain RSO annotation pipeline | RGD Automated Pipelines |
4. | Impact of nephron number dosing on cardiorenal damage and effects of ACE inhibition. | Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. |
5. | Genetic low nephron number hypertension is associated with dysregulation of the hepatic and renal insulin-like growth factor system during nephrogenesis. | Rothermund L, etal., J Hypertens. 2006 Sep;24(9):1857-64. doi: 10.1097/01.hjh.0000242411.50536.b9. |
6. | MWF rats with spontaneous albuminuria inherit a reduced efficiency of nephron induction during early nephrogenesis in comparison to SHR rats. | Schulte L, etal., J Hypertens. 2012 Oct;30(10):2031-8. doi: 10.1097/HJH.0b013e328356a60a. |
7. | Protective effect of female gender on the development of albuminuria in a polygenetic rat model is further enhanced by replacement of a major autosomal QTL. | Schulz A, etal., Clin Sci (Lond). 2007 Oct 22;. |
8. | Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage. | Schulz A, etal., Elife. 2019 Mar 22;8. pii: 42068. doi: 10.7554/eLife.42068. |
9. | Genetic dissection of increased urinary albumin excretion in the munich wistar fromter rat. | Schulz A, etal., J Am Soc Nephrol 2002 Nov;13(11):2706-14. |
10. | A major gene locus links early onset albuminuria with renal interstitial fibrosis in the MWF rat with polygenetic albuminuria. | Schulz A, etal., J Am Soc Nephrol 2003 Dec;14(12):3081-9. |
11. | Development of overt proteinuria in the Munich Wistar Fromter rat is suppressed by replacement of chromosome 6 in a consomic rat strain. | Schulz A, etal., J Am Soc Nephrol. 2007 Jan;18(1):113-21. Epub 2006 Dec 13. |
12. | Nephron deficit is not required for progressive proteinuria development in the Munich Wistar Fromter rat. | Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. |
13. | A genetic locus on MWF rat chromosome 6 affects kidney damage in response to L-NAME treatment in spontaneously hypertensive rats. | Schulz A, etal., Physiol Genomics. 2010 Apr 13. |
14. | Dissecting the genetic predisposition to albuminuria and endothelial dysfunction in a genetic rat model. | Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. |
Symbol | Name | Trait |
Bp145 | Blood pressure QTL 145 |
arterial blood pressure trait (VT:2000000)
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Bp146 | Blood pressure QTL 146 |
arterial blood pressure trait (VT:2000000)
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Bp147 | Blood pressure QTL 147 |
arterial blood pressure trait (VT:2000000)
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Glom1 | Glomerulus QTL 1 |
kidney glomerulus morphology trait (VT:0005325)
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Glom2 | Glomerulus QTL 2 |
kidney glomerulus morphology trait (VT:0005325)
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Glom3 | Glomerulus QTL 3 |
kidney glomerulus morphology trait (VT:0005325)
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Uae1 | Urinary albumin excretion QTL 1 |
urine albumin amount (VT:0002871)
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Uae2 | Urinary albumin excretion QTL 2 |
urine albumin amount (VT:0002871)
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Uae3 | Urinary albumin excretion QTL 3 |
urine albumin amount (VT:0002871)
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Uae4 | Urinary albumin excretion QTL 4 |
urine albumin amount (VT:0002871)
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Note Type | Note | Reference |
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strain_anatomy | The strain exhibits an increased number of surface glomeruli. | 634618 |
strain_characteristics | Females have lower blood pressure, mild albuminuria and no signs of glomerulosclerosis | 1642911 |
strain_life_disease | Develops mild hypertension and an increased urinary albumin excretion as compared to a normal Lewis rat. | 634618 |
strain_life_disease | The development of protenuric renal disease is accelerated and increased in the males. | 634618 |
strain_life_disease | The development of protenuric renal disease is accelerated and increased in the males. | 730279 |
strain_phys_biochem | Have a lower number of nephrons as compared to other strains. | 634618 |