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Strain Registration

Strain: DA.BN-(D9Wox24-D9Rat20)/Kini

Symbol: DA.BN-(D9Wox24-D9Rat20)/Kini
Strain: DA.BN-(D9Wox24-D9Rat20)
Substrain: Kini
RGD ID: 7241243
Citation ID: RRID:RGD_7241243
Ontology ID: RS:0003405
Previously known as: DA.BN-Eae4; NBRP Rat No: 0683; DA.BN-(D9Wox24-D9Rat20)/Kini; DA.BN
Type: congenic
Source: Center for Molecular Medicine, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden, National BioResource Project for the Rat in Japan
Origin: DA/ZtmKini females were mated with BN/Rj males, speed congenic strategy was used to generate these congenics; when the donor genome outside of the congenic segment was removed, two heterozygous animals were intercrossed to produce homozygous rats
Coat Color: agouti
Last Known Status: Cryopreserved Sperm
Research Usage Neurobiology
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.291,024,537 - 50,062,324RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0910,869,391 - 54,978,814RGD_MAPPER_PIPELINERnor6.0
Rnor_5.099,858,502 - 54,685,631RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4947,129,152 - 47,129,300RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis. Jagodic M, etal., Sci Transl Med. 2009 Dec 9;1(10):10ra21. doi: 10.1126/scitranslmed.3000278.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D9Wox24)
Rat AssemblyChrPosition (strand)Source
mRatBN7.291,024,537 - 1,024,636 (-)MAPPER
Rnor_6.0910,869,391 - 10,869,489NCBI
Rnor_5.099,858,502 - 9,858,600UniSTS
Celera97,483,005 - 7,483,103UniSTS
Cytogenetic Map9q11UniSTS

Flank 2 / 1 (D9Rat20)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2950,062,176 - 50,062,324 (+)MAPPER
Rnor_6.0954,978,667 - 54,978,814NCBI
Rnor_5.0954,685,484 - 54,685,631UniSTS
RGSC_v3.4947,129,153 - 47,129,300UniSTS
RGSC_v3.4947,129,152 - 47,129,300RGD
RGSC_v3.1947,130,566 - 47,130,714RGD
Celera947,708,231 - 47,708,370UniSTS
SHRSP x BN Map941.0298UniSTS
SHRSP x BN Map941.0298RGD
FHH x ACI Map935.71RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Protection against experimental autoimmune encephalomyelitis (EAE) compared to the susceptible parental DA strain, regulation of proinflammatory T cell activation and regulatory T cells. 1302502
strain_reproduction Good breeding performance 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-18 DA.BN-(D9Wox24-D9Rat20)/Kini    DA.BN-(D9Wox24-D9Rat20)/Kini    Name updated 68913 APPROVED
2014-04-18 DA.BN-(D9Wox24-D9Rat20)/Kini    DA.BN-(D9Wox24-D9Rat20)/Kini    Name updated 68913 APPROVED