Strain Report - Rat Genome Database

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Strain: LEW-Rag1em1Ztm

Symbol: LEW-Rag1em1Ztm
Strain: LEW-Rag1em1
Substrain: Ztm
RGD ID: 7204133
Citation ID: RRID:RGD_7204133
Ontology ID: RS:0003367
Alleles: Rag1em1Ztm
Previously known as: LEW-Rag1em1Ztm
Type: mutant
Source: Zentrales Tierlaboratorium, Medizinische Hochschule Hannover, Germany
Origin: This strain was produced by injecting ZFNs into LEW/Ztm rat embryos. The resulting mutation is a 4-bp frameshift deletion in exon 2.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2387,917,061 - 87,928,158RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0391,206,394 - 91,217,491RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0397,866,048 - 97,877,145RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4386,780,782 - 86,791,878RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat. Zschemisch NH, etal., BMC Immunol. 2012 Nov 8;13:60. doi: 10.1186/1471-2172-13-60.

Region

Rat Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type
Rag1em1Ztm-var1 chr3 87922910 87922913 TTCC - deletion
Rag1em1Ztm-var1 chr3 91212243 91212246 TTCC - deletion

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_reproduction Heterozygous mutants show normal reproduction; 6-12 pups per litter 7204131

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-03 LEW-Rag1em1Ztm    LEW-Rag1em1Ztm    Symbol updated 68687 APPROVED
2014-04-03 LEW-Rag1em1Ztm    LEW-Rag1em1Ztm    Symbol updated 68687 APPROVED
2014-04-03 LEW-Rag1em1Ztm    LEW-Rag1em1Ztm    Name updated 68913 APPROVED
2014-04-03 LEW-Rag1em1Ztm    LEW-Rag1em1Ztm    Name updated 68913 APPROVED
2012-12-17 LEW-Rag1em1Ztm    LEW-Rag1em1Ztm    Name updated 68913 APPROVED
2012-12-17 LEW-Rag1em1Ztm    LEW-Rag1em1Ztm    Name updated 68913 APPROVED