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Strain Registration

Strain: HXB-1-43/Ipcv

Symbol: HXB-1-43/Ipcv
Strain: SHR, BN-Lx
Substrain: OlaIpcv, Lx/Cub
RGD ID: 68049
Citation ID: RRID:RGD_68049
Ontology ID: RS:0000403
Previously known as: (SHR/OlaIpcvx BN-Lx/Cub)F2 x 20-45
Type: recombinant_inbred
Source: Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.166 NL-3508 TD Utrecht, Netherlands
Origin: Set of 17 recombinant inbred strains developed by Pravenec, Klir and Kren from a cross between SHR/OlaIpcv and BN.Lx/CubIpcv, and described by Pravenec et al (1988). Strains have now been typed at 500 loci and scanned for quantitative trait loci associated with blood pressure and heart weight (Pravenec et al, 1995). These recombinant inbred strains are derived from the (SHR/OlaIpcvx BN-Lx/Cub)F2 pairs.
Inbred Generations: F17-21 (Ipcv 1988)
Last Known Status: Unknown





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
HXB-1-43/Ipcv  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
liver cholesterol amount  EXP 629576 RGD 
liver copper amount  EXP 619607 RGD 


References

References - curated
# Reference Title Reference Citation
1. A genetic and correlation analysis of liver cholesterol concentration in rat recombinant inbred strains fed a high cholesterol diet. Bottger A, etal., Biochem Biophys Res Commun 1998 May 8;246(1):272-5.
2. Genetic and correlation analysis of hepatic copper content in the rat. de Wolf ID, etal., Biochem Biophys Res Commun 2001 Dec 21;289(5):1247-51.
3. Inbred Strains Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
4. Rat Strain List M. Festing Rat Strain List
5. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Hcuc1 Hepatic copper content QTL 1 liver copper amount   (VT:0003065)    
Hcuc2 Hepatic copper content QTL 2 liver copper amount   (VT:0003065)    
Hpcl1 Hepatic cholesterol level QTL 1 liver cholesterol amount   (VT:0010498)    

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-04-20 HXB-1-43/Ipcv    HXB-1-43    Symbol updated 68687 APPROVED
2011-04-20 HXB-1-43/Ipcv    HXB-1-43    Name updated 68913 APPROVED
2011-04-20 HXB-1-43/Ipcv    HXB-1-43    Symbol updated 68687 APPROVED
2011-04-20 HXB-1-43/Ipcv    HXB-1-43    Name updated 68913 APPROVED