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Strain Registration

Strain: SS-Comtem1Mcwi

Symbol: SS-Comtem1Mcwi
Strain: SS-Comtem1
Substrain: Mcwi
RGD ID: 6484561
Citation ID: RRID:RGD_6484561
Ontology ID: RS:0003254
Alleles: Comtem1Mcwi
Also Known As: SS-Comtem1Mcwi; SS-Comt^[em1Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CTGTTCCAGGTCACCATCctcaatGGGGCATCCCAGGATCTT into SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp frameshift deletion in exon 4.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81196,072,371 - 96,091,956RGD_MAPPER_PIPELINE
mRatBN7.21182,568,052 - 82,587,642RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01186,731,828 - 86,731,841RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01189,809,853 - 89,829,568RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41184,561,591 - 84,581,713RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Characterization of a Comt Knock-out Rat for Blood Pressure and Associated Phenotypes. Casati M, etal.,AHA Hypertension Volume 60, Number Suppl_1.A160
2. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Comtem1Mcwi-var1 chr11 86731828 86731841 CTCAATGGGGCATC - deletion Rnor_6.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-31 SS-Comtem1Mcwi    SS-Comtem1Mcwi    Symbol updated 68687 APPROVED
2014-03-31 SS-Comtem1Mcwi    SS-Comtem1Mcwi    Symbol updated 68687 APPROVED
2014-03-31 SS-Comtem1Mcwi    SS-Comtem1Mcwi    Name updated 68913 APPROVED
2014-03-31 SS-Comtem1Mcwi    SS-Comtem1Mcwi    Name updated 68913 APPROVED
2013-08-15 SS-Comtem1Mcwi    SS-Comtem1Mcwi    Name updated 68913 APPROVED
2013-08-15 SS-Comtem1Mcwi    SS-Comtem1Mcwi    Name updated 68913 APPROVED