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Strain Registration

General

Strain: SHR.BN-(D5Wox12-D5Wox20)/Ipcv

Symbol:

SHR.BN-(D5Wox12-D5Wox20)/Ipcv

Strain:

SHR.BN-(D5Wox12-D5Wox20)

Substrain:

Ipcv

RGD ID:

634382

Citation ID:

RRID:RGD_634382

Ontology ID:

RS:0000723

Also Known As:

SHR-5; SHR.BN-(D5Wox12-D5Wox20)/Ipcv; SHR/OlaIpcv.BN/Crj-(D5Wox12-D5Wox20)

Type:

congenic

Available Source:

Not Available

Origination:

Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

Description:

This congenic strain carries a BN/Crl chromosome 5 segment transferred to the SHR/OlaIpcv background

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	139,989,554 - 139,989,768	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	5	145,726,049 - 145,726,262	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	5	149,494,416 - 149,494,629	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	5	147,065,698 - 147,065,912	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased kidney weight (IAGP)

decreased systemic arterial systolic blood pressure (IAGP)

increased body weight (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

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Clinical Measurement

body weight

both kidneys wet weight to body weight ratio

References

References - curated

#	Reference Title	Reference Citation
1.	Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat.	Pravenec M, etal., Physiol Res 2003;52(3):285-9.
2.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D5Rat63)

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	145,274,041 - 145,274,255 (+)	Marker Load Pipeline
mRatBN7.2	5	139,989,554 - 139,989,768 (+)	MAPPER
Rnor_6.0	5	145,726,049 - 145,726,262	NCBI
Rnor_5.0	5	149,494,416 - 149,494,629	UniSTS
RGSC_v3.4	5	147,065,698 - 147,065,912	RGD
RGSC_v3.4	5	147,065,699 - 147,065,912	UniSTS
RGSC_v3.1	5	147,075,738 - 147,075,951	RGD
Celera	5	138,484,465 - 138,484,667	UniSTS
RH 3.4 Map	5	936.6	UniSTS
RH 3.4 Map	5	936.6	RGD
RH 2.0 Map	5	152.9	RGD
SHRSP x BN Map	5	78.5699	RGD

Flank 2 / 1 (D5Wox20)

Rat Assembly	Chr	Position (strand)	Source
RH 3.4 Map	5	727.1	RGD
RH 3.4 Map	5	727.1	UniSTS
RH 2.0 Map	5	661.7	RGD

Strain QTL Data

Symbol	Name	Trait
Bp139	Blood pressure QTL 139	arterial blood pressure trait (VT:2000000)

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_phys_biochem	This congenic strain displays decreased blood pressure compared to the SHR/OlaIpcv parental strain	631851

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: SHR.BN-(D5Wox12-D5Wox20)/Ipcv

Mammalian Phenotype

Related Phenotype Data for Term "SHR.BN-(D5Wox12-D5Wox20)/Ipcv" (RS:0000723)