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Strain Registration

Strain: WKY.SHRSP-(Asgr1-Vamp2)/Bbb

Symbol: WKY.SHRSP-(Asgr1-Vamp2)/Bbb
Strain: WKY.SHRSP-(Asgr1-Vamp2)
Substrain: Bbb
RGD ID: 631601
Citation ID: RRID:RGD_631601
Ontology ID: RS:0001064
Also Known As: WKY.SHRSP-(Asgr1-Vamp2); WKY-1HD; WKY-1; MDC-01-83; WKY.SHRSP-(Asgr1-Vamp2)/Bbb
Type: congenic
Available Source: Not Available
Origination: Max-Delbruck Center for Molecular Medicine, Germany
Description: Both the strains WKY and SHRSP were from University of Heidelberg, Heidelberg, Germany; The SHRSP was originated in 1974 from Okamoto and Aoki
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21053,793,581 - 54,779,642RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01055,675,171 - 56,666,086RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01055,418,231 - 56,411,205RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41055,848,264 - 56,903,173RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10. Kreutz R, etal., Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8778-82.
2. Interaction between blood pressure quantitative trait loci in rats in which trait variation at chromosome 1 is conditional upon a specific allele at chromosome 10. Monti J, etal., Hum Mol Genet 2003 Feb 15;12(4):435-9.
3. Congenic rats for hypertension: how useful are they for the hunting of hypertension genes? Nabika T, etal., Clin Exp Pharmacol Physiol 2000 Apr;27(4):251-6.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.

Region

Position Markers

Flank 1 / 1 (Asgr1)
Rat AssemblyChrPosition (strand)Source
GRCr81055,274,299 - 55,278,323 (+)NCBI
mRatBN7.21054,775,727 - 54,779,642 (+)NCBI
mRatBN7.2 Ensembl1054,776,024 - 54,779,631 (+)Ensembl
UTH_Rnor_SHR_Utx1059,437,984 - 59,441,840 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01058,926,564 - 58,930,426 (+)NCBI
UTH_Rnor_WKY_Bbb_1.01054,433,827 - 54,437,683 (+)NCBI
Rnor_6.01056,662,188 - 56,666,086 (+)NCBI
Rnor_6.0 Ensembl1056,662,242 - 56,666,086 (+)Ensembl
Rnor_5.01056,407,361 - 56,411,205 (+)NCBI
RGSC_v3.41056,899,266 - 56,903,173 (+)NCBI
RGSC_v3.11056,912,888 - 56,916,796 (+)NCBI
Celera1053,929,331 - 53,933,180 (+)NCBI
Cytogenetic Map10q24NCBI

Flank 2 / 1 (Vamp2)
Rat AssemblyChrPosition (strand)Source
GRCr81054,292,423 - 54,296,657 (+)NCBI
mRatBN7.21053,793,581 - 53,797,815 (+)NCBI
mRatBN7.2 Ensembl1053,793,923 - 53,797,809 (+)Ensembl
UTH_Rnor_SHR_Utx1058,455,722 - 58,459,585 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01057,944,320 - 57,948,183 (+)NCBI
UTH_Rnor_WKY_Bbb_1.01053,452,495 - 53,456,350 (+)NCBI
Rnor_6.01055,675,171 - 55,679,405 (+)NCBI
Rnor_6.0 Ensembl1055,675,575 - 55,679,450 (+)Ensembl
Rnor_5.01055,418,231 - 55,422,465 (+)NCBI
RGSC_v3.41055,848,264 - 55,852,132 (+)NCBI
RGSC_v3.11055,861,886 - 55,865,753 (+)NCBI
Celera1052,959,486 - 52,963,354 (+)NCBI
Cytogenetic Map10q24NCBI
Strain QTL Data
Symbol Name Trait
Bp133 Blood pressure QTL 133 arterial blood pressure trait   (VT:2000000)    
Bp134 Blood pressure QTL 134 arterial blood pressure trait   (VT:2000000)    
Bp89 Blood pressure QTL 89 arterial blood pressure trait   (VT:2000000)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Displays higher basal and NaCl-loaded blood pressures than the WKY 619633