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Strain Registration

Strain: LEW.1AV1.DA-(D10Rat92-D10Wox17)/Ubc

Symbol: LEW.1AV1.DA-(D10Rat92-D10Wox17)/Ubc
Strain: LEW.1AV1.DA-(D10Rat92-D10Wox17)
Substrain: Ubc
RGD ID: 631596
Citation ID: RRID:RGD_631596
Ontology ID: RS:0000495
Also Known As: LEW.1AV1.DA-(D10Rat24-D10Wox17)/Ubc; LEW.1AV1.DA-(D10Rat92-D10Wox17)/Ubc
Type: congenic
Available Source: Not Available
Origination: Biomedical Center in Uppsala, Sweden
Description: Congenic substrain derived from intercrosses of the Oia3-congenic strain (LEW.1AV1.DA-(D10Rat20-D10Mgh1)x LEW.1AV1)F2.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21074,585,846 - 87,055,282RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01077,269,759 - 90,042,115RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01077,132,487 - 89,831,596RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41078,170,416 - 91,168,491RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis. Holm BC, etal., Hum Mol Genet 2001 Mar 15;10(6):565-72.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D10Rat92)
Rat AssemblyChrPosition (strand)Source
GRCr81075,082,967 - 75,083,145 (+)Marker Load Pipeline
mRatBN7.21074,585,846 - 74,586,024 (+)MAPPER
Rnor_6.01077,269,759 - 77,269,936NCBI
Rnor_5.01077,132,487 - 77,132,664UniSTS
RGSC_v3.41078,170,416 - 78,170,722RGD
RGSC_v3.41078,170,545 - 78,170,722UniSTS
RGSC_v3.11078,184,915 - 78,185,092RGD
Celera1073,484,939 - 73,485,118UniSTS
RH 3.4 Map10681.2UniSTS
RH 3.4 Map10681.2RGD
SHRSP x BN Map1052.4899UniSTS
SHRSP x BN Map1052.4899RGD
FHH x ACI Map1060.8599RGD

Flank 2 / 1 (D10Wox17)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21087,055,121 - 87,055,282 (+)MAPPER
Rnor_6.01090,041,957 - 90,042,115NCBI
Rnor_5.01089,831,438 - 89,831,596UniSTS
RGSC_v3.41091,168,332 - 91,168,491RGD
RGSC_v3.41091,168,333 - 91,168,491UniSTS
RGSC_v3.11091,182,702 - 91,182,861RGD
Celera1085,772,728 - 85,772,886UniSTS
RH 3.4 Map10887.4UniSTS
RH 3.4 Map10887.4RGD
RH 2.0 Map10991.0RGD
Cytogenetic Map10q32.1UniSTS
Strain QTL Data
Symbol Name Trait
Oia4 Oil induced arthritis QTL 4 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems Displays increased genetic susceptibility to the induction of arthritis by squalene injection. 62404
strain_immunology Exhibits T lymphocyte infiltration into joints following subdermal squaline injection. 62404
strain_life_disease Displays a somewhat increased genetically susceptible to induction of arthritis by injection of adjuvant oil squalene, susceptibility is less than that of congenic substrains containing related QTLS 3b and 3c. 62404

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-28 LEW.1AV1.DA-(D10Rat92-D10Wox17)/Ubc    LEW.1AV1.DA-(D10Rat92-D10Wox17)/Ubc    Name updated 68913 APPROVED
2013-08-28 LEW.1AV1.DA-(D10Rat92-D10Wox17)/Ubc    LEW.1AV1.DA-(D10Rat92-D10Wox17)/Ubc    Name updated 68913 APPROVED