Strain Report - Rat Genome Database

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Strain: LEW.1AV1.DA-(D10Rat92-D10Rat135)/Ubc

Symbol: LEW.1AV1.DA-(D10Rat92-D10Rat135)/Ubc
Strain: LEW.1AV1.DA-(D10Rat92-D10Rat135)
Substrain: Ubc
RGD ID: 631595
Citation ID: RRID:RGD_631595
Ontology ID: RS:0000494
Also Known As: LEW.1AV1.DA-(D10Rat20-D10Mgh1)/Ubc; LEW.1AV1.DA-(D10Rat92-D10Rat135)/Ubc
Type: congenic
Available Source: Not Available
Origination: Biomedical Center in Uppsala, Sweden
Description: LEW.1AV1 x DA F1 was backcrossed to LEW.1AV1 for 9 generations with selection for the Oia3 locus using flanking markers, then F1N9F1 rats were used as founders for the Oia3 congenic strain.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21074,585,846 - 104,670,812RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01077,269,759 - 108,540,162RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01077,132,487 - 108,145,987RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41078,170,416 - 108,776,963RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype


References - curated
# Reference Title Reference Citation
1. Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis. Holm BC, etal., Hum Mol Genet 2001 Mar 15;10(6):565-72.
2. Identification of rat susceptibility loci for adjuvant-oil-induced arthritis. Lorentzen JC, etal., Proc Natl Acad Sci U S A 1998 May 26;95(11):6383-7
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Position Markers

Flank 1 / 1 (D10Rat92)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21074,585,846 - 74,586,024 (+)MAPPER
Rnor_6.01077,269,759 - 77,269,936NCBI
Rnor_5.01077,132,487 - 77,132,664UniSTS
RGSC_v3.41078,170,545 - 78,170,722UniSTS
RGSC_v3.41078,170,416 - 78,170,722RGD
RGSC_v3.11078,184,915 - 78,185,092RGD
Celera1073,484,939 - 73,485,118UniSTS
RH 3.4 Map10681.2RGD
RH 3.4 Map10681.2UniSTS
SHRSP x BN Map1052.4899UniSTS
SHRSP x BN Map1052.4899RGD
FHH x ACI Map1060.8599RGD

Flank 2 / 1 (D10Rat135)
Rat AssemblyChrPosition (strand)Source
mRatBN7.210104,670,657 - 104,670,812 (+)MAPPER
Rnor_6.010108,540,008 - 108,540,162NCBI
Rnor_5.010108,145,833 - 108,145,987UniSTS
RGSC_v3.410108,776,808 - 108,776,963RGD
RGSC_v3.410108,776,809 - 108,776,963UniSTS
RGSC_v3.110108,791,287 - 108,791,662RGD
Celera10103,216,256 - 103,216,410UniSTS
RH 2.0 Map101397.5RGD
SHRSP x BN Map1094.1199RGD
Cytogenetic Map10q32.3UniSTS
Strain QTL Data
Symbol Name Trait
Oia3 Oil induced arthritis QTL 3 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems Genetically susceptible to induction of arthritis by squalene injection. 62404
strain_immunology Exhibit T lymphocyte infiltration into joints following subdermal squaline injection. 62404
strain_life_disease Displays genetic susceptibility to induction of arthritis by injection of adjuvant oil squalene. 62404