Strain Report - Rat Genome Database

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Strain: LEW/OlaHsd

Symbol: LEW/OlaHsd
Strain: LEW
Substrain: OlaHsd
RGD ID: 631579
Citation ID: RRID:RGD_631579
Ontology ID: RS:0000525
Type: inbred
Available Source: Harlan France
Origination: Harlan France
Description: Obtained from Harlan UK, and for this study kept at the Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Quantitative trait loci influencing blood and liver cholesterol concentration in rats. Bonne AC, etal., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9.
2. Quantitative trait loci influencing hepatic copper in rats. de Wolf ID, etal., Exp Biol Med (Maywood) 2002 Jul;227(7):529-34.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Strain QTL Data
Symbol Name Trait
Bw6 Body weight QTL 6 body mass   (VT:0001259)    
Bw7 Body weight QTL 7 body mass   (VT:0001259)    
Hcuc3 Hepatic copper content QTL 3 liver copper amount   (VT:0003065)    
Hcuc4 Hepatic copper content QTL 4 liver copper amount   (VT:0003065)    
Sald1 Serum aldosterone level QTL 1 blood aldosterone amount   (VT:0005346)    
Sald2 Serum aldosterone level QTL 2 blood aldosterone amount   (VT:0005346)    
Scl6 Serum cholesterol level QTL 6 blood cholesterol amount   (VT:0000180)    
Scl7 Serum cholesterol level QTL 7 blood cholesterol amount   (VT:0000180)    
Scl8 Serum cholesterol level QTL8 blood cholesterol amount   (VT:0000180)    
Scl9 Serum cholesterol level QTL 9 blood cholesterol amount   (VT:0000180)    
Spl2 Serum phospholipid level QTL 2 blood phospholipid amount   (VT:0006084)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Differs from BC/Cpbu rats in blood and hepatic cholesterol levels before and after a cholesterol -rich diet. These have a lower serum cholesterol level than BC/Cpbu rats. 629577
strain_characteristics Have a higher body weight than the BC/Cpbu rats. 629577

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-09-26 LEW/OlaHsd    LEW/OlaHsd    Name updated 68913 APPROVED
2014-09-26 LEW/OlaHsd    LEW/OlaHsd    Name updated 68913 APPROVED