Phenotype Values via Phenominer Click to see Annotation Detail View
Related Phenotype Data for Term "SS-Chr 7BN/Mcwi" (RS:0000807)
Phenotype Annotations Click to see Annotation Detail View
Phenotype Values via PhenoMiner Click to see Annotation Detail View
|Clinical Measurement||heart rate||left ventricular diastolic blood pressure||left ventricular systolic blood pressure||mean arterial blood pressure||body weight||body temperature||left ventricular developed pressure||red blood cell count||blood hemoglobin level||blood neutrophil count||blood lymphocyte count||blood monocyte count||blood eosinophil count||hematocrit||mean corpuscular volume||plasma anion gap||heart wet weight||heart weight to body weight ratio||lung dry weight to body weight ratio||heart right ventricle weight to left ventricle weight ratio||plasma renin activity level||minute ventilation||arterial blood flow rate||tidal volume||partial pressure of blood carbon dioxide (Pco2)||percent change in ventilation||respiration rate||mean corpuscular hemoglobin||mean corpuscular hemoglobin concentration||absolute change in partial pressure of blood carbon dioxide||absolute change in partial pressure of blood oxygen||absolute change in blood pH||serum total cholesterol level||total white blood cell count||serum total bilirubin level||blood pH||partial pressure of blood oxygen||serum bicarbonate level||serum chloride level||serum potassium level||serum sodium level||serum calcium level||percent change in respiration rate||percent change in tidal volume||absolute change in mean arterial blood pressure||absolute change in heart rate||plasma creatinine level||serum phosphate level||serum glucose level||serum albumin level||serum alanine aminotransferase activity level||serum alkaline phosphatase activity level||serum aspartate aminotransferase activity level||serum urea nitrogen level||serum total protein level||time to onset of heart contraction||time to peak heart contraction||heart contraction pressure||heart left ventricle infarction weight to total heart left ventricle weight ratio||absolute change in body temperature||calculated pulmonary vascular resistance normalized to body weight||FAPGG metabolism-surface area product||methylene blue metabolism-surface area product without auto-oxidation||methylene blue metabolism-surface area product after auto-oxidation||methylene blue to FAPGG metabolism-surface area product ratio||dose of methacholine at which pulmonary conductance is half its pretreatment value||fractional change in blood vessel diameter per unit change in intravascular pressure||concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)||logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)||concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)||logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)||concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)||logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)||maximum contractile force per wet weight of aorta||acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel||sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel||hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel||percent change in heart rate||percent change in arterial blood flow rate||percent change in left ventricular developed pressure||percent change in left ventricular systolic blood pressure||urine total protein excretion rate||urine albumin excretion rate||urine sodium excretion rate||urine potassium excretion rate||creatinine clearance||heart effluent lactate dehydrogenase activity level normalized to heart weight||serum globulin level|
|#||Reference Title||Reference Citation|
|1.||Sex-Specific Differences in Chromosome-Dependent Regulation of Vascular Reactivity in Female Consomic Rat Strains from a SS x BN Cross.||Kunert MP, etal., Am J Physiol Regul Integr Comp Physiol. 2008 May 28;.
|2.||Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat.||Kunert MP, etal., Physiol Genomics. 2006 Aug 16;26(3):218-25. Epub 2006 Jun 13.
|3.||Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease.||Mattson DL, etal., Am J Physiol Renal Physiol. 2008 Sep;295(3):F837-42. Epub 2008 Jul 23.
|4.||PhysGen Strains||PhysGen strains
|5.||RGD Strain RSO annotation pipeline||RGD Automated Pipelines
|6.||Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains.||Wiessner JH, etal., Am J Physiol Renal Physiol. 2009 Aug;297(2):F301-6. Epub 2009 Jun 3.
|strain_drgs_chems||The aortic rings of animals on low-salt diet and high salt diet were more sensitive to phenylephrine as compared to the parental SS.||1598768|
|strain_life_disease||The blood pressure of females is 120 mmHg and of males is 112 mmHg.||629526|
|strain_other||The average weight of females is 191g and of males 274g.||629526|
|strain_reproduction||The average litter size is 8.3 pups and the average generation time is 40 days.||629526|
|Date||Current Symbol||Current Name||Previous Symbol||Previous Name||Description||Reference||Status|
|2013-08-12||SS-Chr 7BN/Mcwi||SS-Chr 7BN/Mcwi||Name updated||68913||APPROVED|