Strain Report - Rat Genome Database

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Strain: DA/Slc

Symbol: DA/Slc
Strain: DA
Substrain: Slc
Full Name: dark agouti
RGD ID: 61111
Citation ID: RRID:RGD_61111
Ontology ID: RS:0000247
Also known as: NBRP Rat No: 0157; MDC-02-72
Type: inbred
Source: National BioResource Project for the Rat in Japan
Origin: These were produced by from SD parents in 1984 by hysterectomy and fostering, then moved to Kumamoto University of Medicine in 1983.
Coat Color: Agouti
Inbred Generations: F48
Last Known Status: Live Animals





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
kidney wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
single kidney wet weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
urine total protein excretion rate
both testes wet weight to body weight ratio
urine sodium excretion rate to body weight ratio
squamous cell carcinoma of the tongue maximum tumor diameter
squamous cell carcinoma of the head and neck tumor number
non-tongue squamous cell carcinoma of the head and neck tumor number
squamous cell carcinoma of the tongue tumor number
number of squamous cell tumors of the tongue with diameter greater than 5 mm
post-insult time to onset of moribundity
number of squamous cell tumors of the tongue with diameter greater than 3 mm
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio

References


Region

Cell Lines
Symbol
DA/Slc-ES1/Nips
DA/Slc-ES2/Nips

Strain QTL Data
Symbol Name Trait
Kidm41 Kidney mass QTL 41 kidney mass   (VT:0002707)    
Pur17 Proteinuria QTL 17 urine protein amount   (VT:0005160)    
Tcas1 Tongue tumor susceptibility QTL 1 tongue integrity trait   (VT:0010553)    
Tcat1 Tongue tumor resistance QTL 1 tongue integrity trait   (VT:0010553)    
Tspe1 Trichinella spiralis expulsion QTL 1 parasite quantity   (VT:0010441)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_infection displays strong host response to intestinal nematode parasite Trichinella spiralis infection with expulsion of intestinal worms 1578305
strain_life_disease These are susceptible to allergic encephalomyelitis, collagen induced arthritis and other auto-immune diseases. 61091

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-10 DA/Slc  dark agouti  DA/Slc  dark agouti  Name updated 68913 APPROVED