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Strain Registration

Strain: SHR/Mol

Symbol: SHR/Mol
Strain: SHR
Substrain: Mol
RGD ID: 61110
Citation ID: RRID:RGD_61110
Ontology ID: RS:0000749
Previously known as: MDC-01-79
Type: inbred
Source: Mollegaard Breeding Centre Ltd., Denmark
Origin: Spontaneously hypertensive rat, maintained at the Mollegaard breeding center, displays traits of hypertension but not to diabetes.
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Mapping of novel genes predisposing or protecting diabetes development in the BB/OK rat. Kloting I, etal., Biochem Biophys Res Commun 1998 Apr 17;245(2):483-6
2. Quantitative trait loci for body weight, blood pressure, blood glucose, and serum lipids: linkage analysis with wild rats (Rattus norvegicus). Kloting I, etal., Biochem Biophys Res Commun 2001 Jun 29;284(5):1126-33.
3. Quantitative trait loci for blood glucose confirm diabetes predisposing and protective genes, Iddm4 and Iddm5r, in the spontaneously diabetic BB/OK rat. Kloting I, etal., Int J Mol Med. 1998 Nov;2(5):597-601.
4. Quantitative trait loci on chromosomes 1 and 4 affect lipid phenotypes in the rat. Kovacs P and Kloting I, Arch Biochem Biophys 1998 Jun 1;354(1):139-43.
5. Mapping of quantitative trait loci for body weight on chromosomes 1 and 4 in the rat. Kovacs P and Kloting I, Biochem Mol Biol Int 1998 Feb;44(2):399-405.
6. Novel quantitative trait loci for blood pressure and related traits on rat chromosomes 1, 10, and 18. Kovacs P, etal., Biochem Biophys Res Commun 1997 Jun 18;235(2):343-8
7. Alleles of the spontaneously hypertensive rat decrease blood pressure at loci on chromosomes 4 and 13. Kovacs P, etal., Biochem Biophys Res Commun 1997 Sep 18;238(2):586-9.
8. Congenic strain confirms putative quantitative trait locus for body weight in the rat. Kovacs P, etal., Mamm Genome 1998 Apr;9(4):294-6.
9. RGD Strain RSO annotation pipeline RGD Automated Pipelines
10. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.

Region

Strain QTL Data
Symbol Name Trait
Bp101 Blood pressure QTL 101 arterial blood pressure trait   (VT:2000000)    
Bp102 Blood pressure QTL 102 arterial blood pressure trait   (VT:2000000)    
Bp103 Blood pressure QTL 103 arterial blood pressure trait   (VT:2000000)    
Bp104 Blood pressure QTL 104 arterial blood pressure trait   (VT:2000000)    
Bp42 Blood pressure QTL 42 arterial blood pressure trait   (VT:2000000)    
Bp43 Blood pressure QTL 43 arterial blood pressure trait   (VT:2000000)    
Bp44 Blood pressure QTL 44 arterial blood pressure trait   (VT:2000000)    
Bp45 Blood pressure QTL 45 arterial blood pressure trait   (VT:2000000)    
Bp46 Blood pressure QTL 46 arterial blood pressure trait   (VT:2000000)    
Bp47 Blood pressure QTL 47 arterial blood pressure trait   (VT:2000000)    
Bp48 Blood pressure QTL 48 arterial blood pressure trait   (VT:2000000)    
Bp79 Blood pressure QTL 79 arterial blood pressure trait   (VT:2000000)    
Bp80 Blood pressure QTL 80 arterial blood pressure trait   (VT:2000000)    
Bw10 Body weight QTL 10 body mass   (VT:0001259)    
Bw11 Body weight QTL 11 body mass   (VT:0001259)    
Bw18 Body weight QTL 18 body mass   (VT:0001259)    
Bw20 Body weight QTL 20 body mass   (VT:0001259)    
Bw22 Body weight QTL 22 body mass   (VT:0001259)    
Bw39 Body weight QTL 39 body mass   (VT:0001259)    
Gluco31 Glucose level QTL 31 blood glucose amount   (VT:0000188)    
Iddm10 Insulin dependent diabetes mellitus QTL 10 blood glucose amount   (VT:0000188)    
Iddm8 Insulin dependent diabetes mellitus QTL 8 blood glucose amount   (VT:0000188)    
Iddm9 Insulin dependent diabetes mellitus QTL 9 blood glucose amount   (VT:0000188)    
Scl11 Serum cholesterol level QTL 11 blood cholesterol amount   (VT:0000180)    
Scl22 Serum cholesterol level QTL 22 blood cholesterol amount   (VT:0000180)    
Scl4 Serum cholesterol level QTL 4 blood cholesterol amount   (VT:0000180)    
Scl5 Serum cholesterol level QTL 5 blood cholesterol amount   (VT:0000180)    
Sprol1 Serum protein level QTL 1 blood total protein amount   (VT:0005567)    
Stl1 Serum triglyceride level QTL 1 blood triglyceride amount   (VT:0002644)    
Stl2 Serum triglyceride level QTL 2 blood triglyceride amount   (VT:0002644)    

Additional Information