Strain Report - Rat Genome Database

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Strain: SS-Mmp2em1Mcwi-/-

Symbol: SS-Mmp2em1Mcwi-/-
Strain: SS-Mmp2em1-/Mmp2em1-
Substrain: Mcwi
Full Name: SS-Mmp2em1Mcwi-/Mmp2em1Mcwi-
RGD ID: 5688030
Citation ID: RRID:RGD_5688030
Ontology ID: RS:0003141
Alleles: Mmp2em2Mcwi
Also Known As: SS-Mmp2em1Mcwi-/-; SS-Mmp2em1Mcwi/1Mcwi; SS-Mmp2em1Mcwi/1Mcwi; SS-Mmp2em1Mcwi-/Mmp2em1Mcwi-; SS-Mmp2^[em1Mcwi-/-]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offspring which were intercrossed and offspring maintained as homozygous and heterozygous breeders.
Genetic Status: Homozygous
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21914,154,657 - 14,182,870RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01915,542,771 - 15,570,589RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01926,646,695 - 26,646,702RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41915,246,036 - 15,275,061RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. Knockout of Matrix Metalloproteinase 2 Opposes Hypertension- and Diabetes-Induced Nephropathy. Hirata T, etal., J Cardiovasc Pharmacol. 2023 Aug 25. doi: 10.1097/FJC.0000000000001473.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-31 SS-Mmp2em1Mcwi-/-  SS-Mmp2em1Mcwi-/Mmp2em1Mcwi-  SS-Mmp2em1Mcwi-/-  SS-Mmp2em1Mcwi-/Mmp2em1Mcwi-  Symbol and/or name change 68913 APPROVED