Strain Report - Rat Genome Database

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Strain: SS-Plekha7em4Mcwi-/-

Symbol: SS-Plekha7em4Mcwi-/-
Strain: SS-Plekha7em4-/Plekha7em4-
Substrain: Mcwi
Full Name: SS-Plekha7em4Mcwi-/Plekha7em4Mcwi-
RGD ID: 5686758
Citation ID: RRID:RGD_5686758
Ontology ID: RS:0003088
Alleles: Plekha7em4Mcwi
Also Known As: SS-Plekha7em4Mcwi-/-; SS-Plekha7em4Mcwi/1Mcwi; SS-Plekha7em4Mcwi/1Mcwi; SS-Plekha7em4Mcwi-/Plekha7em4Mcwi-; SS-Plekha7^[em4Mcwi-/-]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Genetic Status: Homozygous
Last Known Status: Live Animals; Cryopreserved Sperm (as of 2018-09-05)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21170,420,191 - 170,420,209RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01185,483,638 - 185,483,656RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01192,397,589 - 192,463,974RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41174,249,022 - 174,316,226RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Endres BT, etal., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.
2. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-27 SS-Plekha7em4Mcwi-/-  SS-Plekha7em4Mcwi-/Plekha7em4Mcwi-  SS-Plekha7em4Mcwi-/-  SS-Plekha7em4Mcwi-/Plekha7em4Mcwi-  Symbol and/or name change 68913 APPROVED