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Strain Registration

Strain: SS-Mstnem1Mcwi-/-

Symbol: SS-Mstnem1Mcwi-/-
Strain: SS-Mstnem1-/Mstnem1-
Substrain: Mcwi
Full Name: SS-Mstnem1Mcwi-/Mstnem1Mcwi-
RGD ID: 5686713
Citation ID: RRID:RGD_5686713
Ontology ID: RS:0003068
Alleles: Mstnem1Mcwi
Also Known As: SS-Mstnem1Mcwi-/-; SS-Mstnem1Mcwi/1Mcwi; SS-Mstnem1Mcwi/1Mcwi; SS-Mstnem1Mcwi-/Mstnem1Mcwi-; SS-Mstn^[em1Mcwi-/-]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Genetic Status: Homozygous
Last Known Status: Cryopreserved Sperm (as of 2019-07-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8955,944,513 - 55,950,913RGD_MAPPER_PIPELINE
mRatBN7.2948,456,663 - 48,456,680RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0953,310,977 - 53,315,804RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0952,977,371 - 52,982,198RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4945,426,831 - 45,431,658RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats. Mendias CL, etal., J Physiol. 2015 Apr 15;593(8):2037-52. doi: 10.1113/jphysiol.2014.287144. Epub 2015 Feb 25.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Mstnem1Mcwi-var1 chr9 48456663 48456680 TTAGAAAGTCAGCTGCAA - deletion mRatBN7.2

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-26 SS-Mstnem1Mcwi-/-  SS-Mstnem1Mcwi-/Mstnem1Mcwi-  SS-Mstnem1Mcwi-/-  SS-Mstnem1Mcwi-/Mstnem1Mcwi-  Symbol and/or name change 68913 APPROVED