Strain Report - Rat Genome Database

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Strain: HotHsd:SD

Symbol: HotHsd:SD
Strain: SD
Substrain: HotHsd
Full Name: Sprague Dawley
RGD ID: 5508397
Citation ID: RRID:RGD_5508397
Ontology ID: RS:0002942
Previously known as: HsdHot:HoltzmanSD; Holtzman
Type: outbred
Source: Envigo
Origin: Originally developed by the Holtzman Company in Madison, Wisconsin, from Sprague Dawley stock in 1947; to Harlan through acquisition in 1986.
Last Known Status: Unknown

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype


References - curated
# Reference Title Reference Citation
1. Strains registered by Harlan Laboratories, Inc. Personal communication with Harlan Laboratories
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity. Van Damme P, etal., Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14825-30. doi: 10.1073/pnas.0705046104. Epub 2007 Sep 5.


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-07 HotHsd:SD  Sprague Dawley  HsdHot:SD  Sprague Dawley  Symbol updated 68687 APPROVED