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Strain Registration

Strain: ACI.BN-(D5Rat113-D5Rat36)/Shul

Symbol: ACI.BN-(D5Rat113-D5Rat36)/Shul
Strain: ACI.BN-(D5Rat113-D5Rat36)
Substrain: Shul
RGD ID: 5135479
Citation ID: RRID:RGD_5135479
Ontology ID: RS:0002616
Also Known As: ACI.BN-Emca8b; Emca8b; ACI.BN-(D5Rat113-D5Rat36)/Shul
Type: congenic
Available Source: Not Available
Origination: Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison
Description: This congenic strain contains a region of BN/SsNHsd chromosome 5 transferred to the ACI/SegHsd strain background
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2573,483,796 - 138,113,774RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0575,809,470 - 143,846,372RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0579,957,402 - 147,610,238RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4576,707,366 - 145,187,034RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Data registered by Dr. James D. Shull's group Personal communication between Dr. James D. Shull's group and the RGD curators
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Mapping of three genetic determinants of susceptibility to estrogen-induced mammary cancer within the Emca8 locus on rat chromosome 5. Schaffer BS, etal., Cancer Prev Res (Phila). 2013 Jan;6(1):59-69. doi: 10.1158/1940-6207.CAPR-12-0346-T. Epub 2012 Nov 14.

Region

Position Markers

Flank 1 / 1 (D5Rat113)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2573,483,796 - 73,483,994 (+)MAPPER
Rnor_6.0575,809,470 - 75,809,667NCBI
Rnor_5.0579,957,402 - 79,957,599UniSTS
RGSC_v3.4576,707,366 - 76,707,563UniSTS
RGSC_v3.4576,707,366 - 76,707,563RGD
RGSC_v3.1576,712,479 - 76,712,676RGD
Celera572,307,346 - 72,307,543UniSTS
RH 3.4 Map5504.5RGD
RH 3.4 Map5504.5UniSTS
SHRSP x BN Map543.4199RGD
SHRSP x BN Map543.4199UniSTS

Flank 2 / 1 (D5Rat36)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25138,113,556 - 138,113,774 (+)MAPPER
Rnor_6.05143,846,157 - 143,846,372NCBI
Rnor_5.05147,610,023 - 147,610,238UniSTS
RGSC_v3.45145,186,818 - 145,187,033UniSTS
RGSC_v3.45145,186,817 - 145,187,034RGD
RGSC_v3.15145,196,810 - 145,197,027RGD
Celera5136,626,405 - 136,626,620UniSTS
RH 3.4 Map5909.5RGD
RH 3.4 Map5909.5UniSTS
RH 2.0 Map5884.1RGD
SHRSP x BN Map576.2899RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease exhibits significantly reduced susceptibility as compared to parental ACI/SegHsd rats 7364727
strain_life_disease number of tumors per rat ranged from 0-4; prolonged latency to appearance of the first palpable tumor; reduced incidence and tumor number as compared to ACI/SegHsd 7364727