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Strain Registration

Strain: ACI.BN-(D5Uwm70-D5Mgh15)/Shul

Symbol: ACI.BN-(D5Uwm70-D5Mgh15)/Shul
Strain: ACI.BN-(D5Uwm70-D5Mgh15)
Substrain: Shul
RGD ID: 5135477
Citation ID: RRID:RGD_5135477
Ontology ID: RS:0002615
Also Known As: ACI.BN-Emca8c; Emca8c; ACI.BN-(D5Uwm70-D5Mgh15)/Shul
Type: congenic
Available Source: Not Available
Origination: Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison
Description: This congenic strain contains a region of BN/SsNHsd chromosome 5 transferred to the ACI/SegHsd strain background
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25161,165,494 - 161,165,651RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05167,739,539 - 167,739,697RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05171,364,494 - 171,364,652RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45167,844,579 - 167,844,737RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Data registered by Dr. James D. Shull's group Personal communication between Dr. James D. Shull's group and the RGD curators
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Mapping of three genetic determinants of susceptibility to estrogen-induced mammary cancer within the Emca8 locus on rat chromosome 5. Schaffer BS, etal., Cancer Prev Res (Phila). 2013 Jan;6(1):59-69. doi: 10.1158/1940-6207.CAPR-12-0346-T. Epub 2012 Nov 14.

Region

Position Markers

Flank 2 / 1 (D5Mgh15)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25161,165,494 - 161,165,651 (+)MAPPER
Rnor_6.05167,739,539 - 167,739,697NCBI
Rnor_5.05171,364,494 - 171,364,652UniSTS
RGSC_v3.45167,844,579 - 167,844,737RGD
RGSC_v3.45167,844,579 - 167,844,737UniSTS
RGSC_v3.15167,854,767 - 167,854,925RGD
RH 3.4 Map51122.3RGD
RH 3.4 Map51122.3UniSTS
RH 2.0 Map51103.8RGD
Cytogenetic Map5 RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease exhibits significantly reduced susceptibility as compared to parental ACI/SegHsd rats 7364727
strain_life_disease number of tumors per rat ranged from 0-4; prolonged latency to appearance of the first palpable tumor; reduced incidence and tumor number as compared to ACI/SegHsd 7364727