Strain Report - Rat Genome Database

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Strain: BN.MES-Cyba/Sna

Symbol: BN.MES-Cyba/Sna
Strain: BN.MES-Cyba
Substrain: Sna
RGD ID: 5135031
Citation ID: RRID:RGD_5135031
Ontology ID: RS:0002611
Also Known As: BN.MES-Cybames; BN.MES-Cybames; BN.MES-Cyba/Sna
Type: congenic
Available Source: Not Available
Origination: Department of Aging Biology, Institute on Aging and Adaptation, Shinshu University, Matsumoto, Japan
Description: mutant Cyba gene from the MES/Slc strain is introduced into the background of BN/SsNSlc by standard procedures with seven backcrosses to BN/SsNSlc
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. BN.MES-Cyba(mes) congenic rats manifest focal necrosis with eosinophilic infiltration in the liver without blood eosinophilia. Tomozawa H, etal., Exp Anim. 2010;59(4):469-78.
3. Genes for difference in eosinophilic phenotype between MES and BN.MES-Cyba(mes) rats are on chromosomes 9, 5, and 1. Tomozawa H, etal., Exp Anim. 2011;60(2):151-60.


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics These have normal blood eosinophil level and robust eosinophil proliferation in the bone marrow. 5134976