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Strain: SS-Cyp1a1em1Mcwi

Symbol: SS-Cyp1a1em1Mcwi
Strain: SS-Cyp1a1em1
Substrain: Mcwi
RGD ID: 5131932
Citation ID: RRID:RGD_5131932
Ontology ID: RS:0002584
Alleles: Cyp1a1em1Mcwi
Also Known As: SS-Cyp1a1em1Mcwi; SS-Cyp1a1^[em1Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CTGGTAACCAACCCTAGGatacagAGAAAGATCCAGGAGGAG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 19-bp frameshift deletion in exon 4.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2858,096,021 - 58,102,130RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0862,476,212 - 62,476,230RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0862,249,046 - 62,255,081RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4861,462,207 - 61,468,237RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Cyp1a1em1Mcwi-var1 chr8 62476212 62476230 GATACAGAGAAAGATCCAG - deletion Rnor_6.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-25 SS-Cyp1a1em1Mcwi    SS-Cyp1a1em1Mcwi    Name updated 68913 APPROVED
2014-03-25 SS-Cyp1a1em1Mcwi    SS-Cyp1a1em1Mcwi    Symbol updated 68687 APPROVED
2014-03-25 SS-Cyp1a1em1Mcwi    SS-Cyp1a1em1Mcwi    Name updated 68913 APPROVED
2014-03-25 SS-Cyp1a1em1Mcwi    SS-Cyp1a1em1Mcwi    Symbol updated 68687 APPROVED
2013-08-13 SS-Cyp1a1em1Mcwi    SS-Cyp1a1em1Mcwi    Name updated 68913 APPROVED