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Strain: WKY.SHRSP-(D1Rat171-D1Wox33)/Izm

Symbol: WKY.SHRSP-(D1Rat171-D1Wox33)/Izm
Strain: WKY.SHRSP-(D1Rat171-D1Wox33)
Substrain: Izm
RGD ID: 4889414
Citation ID: RRID:RGD_4889414
Ontology ID: RS:0002493
Also Known As: NBRP Rat No: 0706; WKY.SHRSP-(D1Rat171-D1Wox33)/Izm; Wpch1.21; WKYpch1.21
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: Department of Functional Pathology, Shimane University School of Medicine, Izumo, Japan
Description: About 100 male pups were obtained by breeding SHRSP/Izm and WKY.SHRSP-(D1Smu13-D1Smu11)/Izm; one pup that had the right recombination was found and backcrossed to the parental strain to get the hetrozygotes, which were then mated brother-sister to get the desired congenic strain
Coat Color: Albino
Inbred Generations: F35
Last Known Status: Cryopreserved Sperm
Research Usage Cardio-Hypertension
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21155,866,514 - 155,866,750RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01166,577,232 - 166,577,467RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01172,767,534 - 174,300,801RGD_MAPPER_PIPELINERnor5.0
Rnor_5.02224,991,853 - 224,991,955RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41158,964,262 - 160,755,065RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.42198,300,754 - 198,300,855RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. A 1.8-Mbp fragment on chromosome 1 affects sympathetic response to stress: evaluation in reciprocal congenic strains between stroke-prone spontaneously hypertensive rat and Wistar-Kyoto rat. Xiao B, etal., J Hypertens. 2010 Nov 8.


Position Markers

Flank 1 / 1 (D1Rat171)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21155,866,514 - 155,866,750 (+)MAPPER
Rnor_6.01166,577,232 - 166,577,467NCBI
Rnor_5.01172,767,534 - 172,767,769UniSTS
RGSC_v3.41158,964,262 - 158,964,498RGD
RGSC_v3.41158,964,263 - 158,964,498UniSTS
RGSC_v3.11159,043,280 - 159,043,515RGD
Celera1153,947,476 - 153,947,711UniSTS
RH 3.4 Map11267.5RGD
RH 3.4 Map11267.5UniSTS
SHRSP x BN Map179.01UniSTS
SHRSP x BN Map179.01RGD
FHH x ACI Map172.14RGD
Cytogenetic Map1q32UniSTS

Flank 2 / 1 (D1Wox33)
Rat AssemblyChrPosition (strand)Source
Rnor_5.02224,991,853 - 224,991,955NCBI
Rnor_5.01174,300,636 - 174,300,801NCBI
RGSC_v3.41160,754,901 - 160,755,065RGD
RGSC_v3.42198,300,754 - 198,300,855RGD
RGSC_v3.12198,263,508 - 198,263,609RGD
RH 3.4 Map11289.0UniSTS
RH 3.4 Map11289.0RGD
Cytogenetic Map1q32UniSTS
Strain QTL Data
Symbol Name Trait
Stresp24 Stress response QTL 24 heart pumping trait   (VT:2000009)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Normal blood pressure. This rat shows stronger sympathetic stress response than WKY. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-27 WKY.SHRSP-(D1Rat171-D1Wox33)/Izm    WKY.SHRSP-(D1Rat171-D1Wox33)/Izm    Name updated 68913 APPROVED