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Strain Registration

Strain: SD-Cyp2dem2(CYP2D6)Kg

Symbol: SD-Cyp2dem2(CYP2D6)Kg
Strain: SD-Cyp2dem2(CYP2D6)
Substrain: Kg
RGD ID: 407446371
Citation ID: RRID:RGD_407446371
Ontology ID: N/A
Also Known As: SD-Cyp2dem2(hCYP2D6 KI); SD-Cyp2d^[em2(CYP2D6)Kg]
Type: mutant
Available Source: The rat strain is deposited to Rat Research and Resource Contact RRRC@missouri.edu for availability.
Origination: Dr. Kristin Grimsrud at University of California, Davis
Description: A ~58.0 kb deletion of the rat Cyp2d gene cluster (1-5) was created using the CRISPR-Cas9 system. Subsequently, the human CYP2D6 gene (~6.2 kb) was inserted in place of the rat Cyp2d gene cluster.
Genetic Status: Homozygous
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2024-08-29)
Research Usage Pharmacogenetics, drug studies





References

References - curated
# Reference Title Reference Citation
1. Strains registration through online submission tool Strains registered through the Online Strain Submission Tool

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