Strain Report - Rat Genome Database

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Strain: HHR/Hat

Symbol: HHR/Hat
Strain: HHR
Substrain: Hat
Full Name: Hirosaki hairless rat
RGD ID: 38676459
Citation ID: RRID:RGD_38676459
Ontology ID: RS:0005037
Type: mutant
Source: Depart of Biochemistry and Genome Biology, Hirosaki Univer-sity School of Medicine
Origin: Hirosaki hairless rat (HHR) is a mutant strain spontaneously derived from Sprague-Dawley rats, and its inheritance is autosomal recessive. . These mutations are autosomal recessive and are suggested to be due to deletion of the keratin gene cluster. HHR attain sexualmaturity at approximately 10 weeks of age and give birth to young but are not able to nurse them.
Genetic Status: Homozygous
Last Known Status: Unknown

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Mammalian Phenotype


References - curated
# Reference Title Reference Citation
1. Nuclear localization of STAT5A modified with O-linked N-acetylglucosamine and early involution in the mammary gland of Hirosaki hairless rat. Nanashima N, etal., J Biol Chem. 2005 Dec 30;280(52):43010-6. Epub 2005 Oct 14.
2. The hairless phenotype of the Hirosaki hairless rat is due to the deletion of an 80-kb genomic DNA containing five basic keratin genes. Nanashima N, etal., J Biol Chem. 2008 Jun 13;283(24):16868-75. Epub 2008 Apr 16.


Additional Information