Strain Report - Rat Genome Database

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Strain: SD-Hamp em4Jfcol -/-

Symbol: SD-Hamp em4Jfcol -/-
Strain: SD-Hamp em4-/-
Substrain: Jfcol
RGD ID: 36174226
Citation ID: RRID:RRRC_00913
Ontology ID: RS:0005017
Alleles: Hamp em4Jfcol
Also Known As: RRRC:00913; SD-Hamp^[ em4Jfcol -/-]
Type: mutant
Available Source: Rat Resource & Research Center (RRRC)
Description: Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em4Jfcol -/- (RGD:36174226) is homozygous carrying a 15-bp deletion in exon 2 of both rat Hamp alleles
Genetic Status: Homozygous
Last Known Status: Cryopreserved Sperm (as of 2020-07-29)
Research Usage This rat models hereditary hemochromatosis (Type 2B) in humans. Iron overload research.
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2186,170,926 - 86,172,865RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0189,368,021 - 89,369,960RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0190,523,506 - 90,525,473RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4185,978,120 - 85,980,059RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Strains registered by Jennifer Lee from University of Florida Strains registered by Jennifer Lee from University of Florida


Additional Information

Database Acc Id Source(s)