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Strain Registration

Strain: LE-Chd8em1Mcwi

Symbol: LE-Chd8em1Mcwi
Strain: LE-Chd8em1
Substrain: Mcwi
RGD ID: 25330088
Citation ID: RRID:RGD_25330088
Ontology ID: RS:0004781
Alleles: Chd8em1Mcwi
Also Known As: LE-Chd8^[em1Mcwi]
Type: mutant
Available Source: Contact MCW rat distribution at mcwcustomrats@mcw.edu
Origination: Generated with support from the Simons Foundation Autism Research Initiative (SFARI); MCW Gene Editing Rat Resource Center
Description: The rat strain was produced by injecting the CRISPR/Cas9 system targeting rat Chd8 gene of Crl:LE embryos. The result is a 5-bp deletion in exon 3 of rat Chd8 gene.
Last Known Status: Live Animals; Cryopreserved Sperm (as of 2021-11-03)
Research Usage Autism, ADHD, Developmental delay, Intellectual disability, Epilepsy, Schizophrenia (from SFARI GENE)
Genotyping Protocol Download Genotyping Protocol
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21524,905,789 - 24,965,461RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01528,646,442 - 28,646,446RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01532,423,198 - 32,482,762RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41527,642,767 - 27,704,443RGD_MAPPER_PIPELINERGSC3.4






References

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Chd8em1Mcwi-var1 chr15 28646442 28646446 CAAGC - deletion Rnor_6.0

Additional Information