Strain Report - Rat Genome Database

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Strain: MWF-Chr 8SHR/Rkb

Symbol: MWF-Chr 8SHR/Rkb
Strain: MWF-Chr 8SHR
Substrain: Rkb
RGD ID: 2312609
Citation ID: RRID:RGD_2312609
Ontology ID: RS:0002073
Previously known as: MWF-Chr 8SHR/Rkb;MWF-8SHR;MWF-8SHR; MWF-Chr 8SHR/Rkb
Type: consomic
Source: Department of Clinical Pharmacology and Toxicology, Charite-Universitatsmedizin Berlin, Berlin, Germany
Origin: MWF/FubRkb male was crossed with female SHR/FubRkb to get F1 animals which in turn were backcrossed with female MWF/FubRkb and the desired consomic selected by marker assisted backcrossing
Last Known Status: Unknown





References

References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. Nephron deficit is not required for progressive proteinuria development in the Munich Wistar Fromter rat. Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease male F1 animals had a significantly higher urinary albumin excretion levels 2312602
strain_life_disease suppressed early onset of albuminuria and diminished proteinuria 2312602