Strain Report - Rat Genome Database

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Pathways

Strain: LEW.1N

Symbol: LEW.1N
Strain: LEW.1N
RGD ID: 2312352
Citation ID: RRID:RGD_2312352
Ontology ID: RS:0002062
Type: congenic
Source: Zentralinstitut fur Versuchstierzucht, Hannover, Germany
Origin: These congenic rats carry the RTln haplotype on the LEW strain genetic background.
Last Known Status: Unknown





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
LEW.1N  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
nervous system integrity trait  EXP 2311085 RGD 

References

References - curated
# Reference Title Reference Citation
1. MHC and non-MHC gene regulation of disease susceptibility and disease course in experimental inflammatory peripheral neuropathy. de Graaf KL, etal., J Neuroimmunol. 2004 Oct;155(1-2):73-84.
2. Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury. Diez M, etal., J Neuroimmunol. 2009 Jun 12.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines
4. Pristane-induced arthritis in rats: a new model for rheumatoid arthritis with a chronic disease course influenced by both major histocompatibility complex and non-major histocompatibility complex genes. Vingsbo C, etal., Am J Pathol 1996 Nov;149(5):1675-83

Region

Strain QTL Data
Symbol Name Trait
Neuinf10 Neuroinflammation QTL 10 nervous system integrity trait   (VT:0010566)    
Neuinf11 Neuroinflammation QTL 11 nervous system integrity trait   (VT:0010566)    
Neuinf12 Neuroinflammation QTL 12 nervous system integrity trait   (VT:0010566)    
Neuinf4 Neuroinflammation QTL 4 nervous system integrity trait   (VT:0010566)    
Neuinf5 Neuroinflammation QTL 5 nervous system integrity trait   (VT:0010566)    
Neuinf6 Neuroinflammation QTL 6 nervous system integrity trait   (VT:0010566)    
Neuinf7 Neuroinflammation QTL 7 nervous system integrity trait   (VT:0010566)    
Neuinf8 Neuroinflammation QTL 8 nervous system integrity trait   (VT:0010566)    
Neuinf9 Neuroinflammation QTL 9 nervous system integrity trait   (VT:0010566)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other these carry the BN MHC haplotype RTln 2311085