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Strain: FHH/EurMcwiCrl

Symbol: FHH/EurMcwiCrl
Strain: FHH
Substrain: EurMcwiCrl
RGD ID: 2311072
Citation ID: RRID:RGD_2311072
Ontology ID: RS:0000178
Type: inbred
Source: Charles River Laboratories
Origin: An outbred stock of fawn hooded rats was introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock until the mid-1980s, when brother x sister mating was initiated by A.P. Provoost to produce two strains designated FHH (also known as FHR) and FHL, which differ in expression of hypertension and proteinuria. The colony was transferred to Erasmus University in Rotterdam, The Netherlands, then to the Medical College of Wisconsin in the 1990s. To Charles River in 2001.
Genetic Markers: Hooded
Coat Color: Fawn
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Is survival time after hemorrhage a heritable, quantitative trait?: an initial assessment. Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.
2. Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1. Newman ZL, etal., PLoS Pathog. 2010 May 20;6(5):e1000906. doi: 10.1371/journal.ppat.1000906.
3. Strains registered by Charles River Laboratories International, Inc. Personal communication with Charles River Laboratories
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. Proteinuria-associated endothelial dysfunction is strain dependent. Ulu N, etal., Am J Nephrol. 2009;30(3):209-17. doi: 10.1159/000218062. Epub 2009 May 5.


Additional Information