Strain Report - Rat Genome Database

Name: SHRSR.SHRSP-( D1Rat134-Mt1-ps1 )/Bbb
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb

Symbol:

SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb

Strain:

SHRSR.SHRSP-(D1Rat134-Mt1-ps1)

Substrain:

Bbb

RGD ID:

2307161

Citation ID:

RRID:RGD_2307161

Ontology ID:

RS:0002193

Previously known as:

SHRsr.SHRsp-(D1Rat134-Mt1pa); SHRSR.SHRSP-(D1Rat134-Mt1pa)/Bbb; MDC-03-48; Stroke congenic IC; SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb; SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb

Type:

congenic

Source:

Max-Delbruck-Center for Molecular Medicine, Berlin, Germany

Origin:

SHRSP were crossed with SHRSR to give heterozygous F₂ animals, these were backcrossed and heterozygotes with desired segment of interest selected and backcrossed to fix the allele of interest

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	133,634,986 - 181,133,270	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	1	141,429,089 - 197,963,072	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	1	142,390,027 - 204,941,832	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	1	135,467,526 - 185,690,396	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

proteinuria (IAGP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased susceptibility to ischemic brain injury (IAGP)

increased urine protein level (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

Options:

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Clinical Measurement

systolic blood pressure

urine total protein excretion rate

percentage of study population developing cerebrovascular lesions during a period of time

References

References - curated

#	Reference Title	Reference Citation
1.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines
2.	Reciprocal congenic lines for a major stroke QTL on rat chromosome 1.	Rubattu S, etal., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.
3.	SNP and haplotype mapping for genetic analysis in the rat.	Saar K, etal., Nat Genet. 2008 May;40(5):560-6.

Region

Position Markers

Flank 1 / 1 (D1Rat134)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	133,634,986 - 133,635,219 (+)	MAPPER
Rnor_6.0	1	141,429,089 - 141,429,321	NCBI
Rnor_5.0	1	142,390,027 - 142,390,259	UniSTS
RGSC_v3.4	1	135,467,527 - 135,467,759	UniSTS
RGSC_v3.4	1	135,467,526 - 135,467,759	RGD
RGSC_v3.1	1	135,545,933 - 135,546,165	RGD
Celera	1	125,698,599 - 125,698,831	UniSTS
RH 3.4 Map	1	1063.1	RGD
RH 3.4 Map	1	1063.1	UniSTS
RH 2.0 Map	1	691.7	RGD
SHRSP x BN Map	1	68.8399	RGD
FHH x ACI Map	1	67.73	RGD
Cytogenetic Map	1	q31	UniSTS

Flank 2 / 1 (Mt1-ps1)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	181,132,896 - 181,133,270 (+)	NCBI
UTH_Rnor_SHR_Utx	1	189,470,813 - 189,471,187 (+)	NCBI
UTH_Rnor_SHRSP_BbbUtx_1.0	1	196,656,898 - 196,657,272 (+)	NCBI
UTH_Rnor_WKY_Bbb_1.0	1	189,337,455 - 189,337,828 (+)	NCBI
Rnor_6.0	1	197,962,698 - 197,963,072 (+)	NCBI
Rnor_5.0	1	204,941,458 - 204,941,832 (+)	NCBI
RGSC_v3.4	1	185,689,821 - 185,690,396 (+)	NCBI
RGSC_v3.1	1	185,839,796 - 185,840,277 (+)	NCBI
Celera	1	178,790,910 - 178,791,284 (+)	NCBI
RH 2.0 Map	1	962.0	RGD
Cytogenetic Map	1	q36	NCBI

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb

Mammalian Phenotype

Related Phenotype Data for Term "SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb" (RS:0002193)