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Strain: DA/ZtmKini

Symbol: DA/ZtmKini
Strain: DA
Substrain: HanKini
RGD ID: 2307156
Citation ID: RRID:RGD_2307156
Ontology ID: RS:0001858
Also Known As: DA Swe; DA/Swe; MDC-01-92; DA/Kini
Type: inbred
Available Source: Not Available
Origination: Center for Molecular Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Description: Substrain of DA, to Hannover after 1965, now at Stockholm, Sweden.
Last Known Status: Unknown

Disease Annotations     Click to see Annotation Detail View


References - curated
# Reference Title Reference Citation
1. The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat. Abdelmagid N, etal., PLoS Pathog. 2012;8(6):e1002753. doi: 10.1371/journal.ppat.1002753. Epub 2012 Jun 28.
2. Mapping and functional characterization of rat chromosome 4 regions that regulate arthritis models and phenotypes in congenic strains. Backdahl L, etal., Arthritis Rheum 2003 Feb;48(2):551-9.
3. Host strain-dependent difference in susceptibility in a rat model of herpes simplex type 1 encephalitis. Bereczky-Veress B, etal., J Neurovirol. 2008 Apr;14(2):102-18. doi: 10.1080/13550280701883832.
4. IL-22RA2 Associates with Multiple Sclerosis and Macrophage Effector Mechanisms in Experimental Neuroinflammation. Beyeen AD, etal., J Immunol. 2010 Dec 1;185(11):6883-6890. Epub 2010 Nov 1.
5. A silent exonic SNP in kdm3a affects nucleic acids structure but does not regulate experimental autoimmune encephalomyelitis. Gillett A, etal., PLoS One. 2013 Dec 3;8(12):e81912. doi: 10.1371/journal.pone.0081912. eCollection 2013.
6. Congenic mapping confirms a locus on rat chromosome 10 conferring strong protection against myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Jagodic M, etal., Immunogenetics 2001 Jul;53(5):410-5.
7. An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. Jagodic M, etal., J Immunol 2004 Jul 15;173(2):1366-73.
8. A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis. Jagodic M, etal., Sci Transl Med. 2009 Dec 9;1(10):10ra21. doi: 10.1126/scitranslmed.3000278.
9. Susceptibility of DA rats to arthritis induced with adjuvant oil or rat collagen is determined by genes both within and outside the major histocompatibility complex. Lorentzen JC and Klareskog L, Scand J Immunol 1996 Dec;44(6):592-8.
10. Identification of rat susceptibility loci for adjuvant-oil-induced arthritis. Lorentzen JC, etal., Proc Natl Acad Sci U S A 1998 May 26;95(11):6383-7
11. Multiple loci comprising immune-related genes regulate experimental neuroinflammation. Marta M, etal., Genes Immun. 2010 Jan;11(1):21-36. Epub 2009 Aug 13.
12. RGD Strain RSO annotation pipeline RGD Automated Pipelines
13. High resolution mapping of an arthritis susceptibility locus on rat chromosome 4, and characterization of regulated phenotypes. Ribbhammar U, etal., Hum Mol Genet 2003 Sep 1;12(17):2087-96.
14. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
15. Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat. Stridh P, etal., PLoS One. 2010 Sep 15;5(9):e12716.


Strain QTL Data
Symbol Name Trait
Bw143 Body weight QTL 143 body mass   (VT:0001259)    
Bw144 Body weight QTL 144 body mass   (VT:0001259)    
Bw145 Body weight QTL 145 body mass   (VT:0001259)    
Eae24 Experimental allergic encephalomyelitis QTL 24 nervous system integrity trait   (VT:0010566)    
Eae25 Experimental allergic encephalomyelitis QTL 25 nervous system integrity trait   (VT:0010566)    
Eae26 Experimental allergic encephalomyelitis QTL 26 nervous system integrity trait   (VT:0010566)    
Eae27 Experimental allergic encephalomyelitis QTL 27 nervous system integrity trait   (VT:0010566)    
Eae35 Experimental allergic encephalomyelitis QTL 35 blood tumor necrosis factor amount   (VT:0008552)    
Vie1 Viral induced encephalitis QTL 1 brain integrity trait   (VT:0010579)    
Vie2 Viral induced encephalitis QTL 2 brain integrity trait   (VT:0010579)    
Vie3 Viral induced encephalitis QTL 3 brain integrity trait   (VT:0010579)    
Vie4 Viral induced encephalitis QTL 4 brain integrity trait   (VT:0010579)    
Vie5 Viral induced encephalitis QTL 5 brain integrity trait   (VT:0010579)    

Additional Information