Strain Report - Rat Genome Database

Name: SHR.BN-( D2Rat226-D2Rat294 )/Jk
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: SHR.BN-(D2Rat226-D2Rat294)/Jk

Symbol:

SHR.BN-(D2Rat226-D2Rat294)/Jk

Strain:

SHR.BN-(D2Rat226-D2Rat294)

Substrain:

RGD ID:

2306895

Citation ID:

RRID:RGD_2306895

Ontology ID:

RS:0002155

Previously known as:

SHR.BN2c; SHR.BN-(D2Rat226-D2Rat294)/Jk; SHR.BN-(D2Rat226-D2Rat294)/Jk

Type:

congenic

Source:

Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, Brazil. Genetica

Origin:

Backcross marker-assisted method was used to fix the BN fragment onto SHR genome, once selection was done using markers, male and female were crossed to get homozygous animals

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	164,073,756 - 227,146,641	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	2	177,680,772 - 243,901,375	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	2	197,020,226 - 262,435,073	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	2	170,338,294 - 236,153,712	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased heart rate (IAGP)

decreased mean systemic arterial blood pressure (IAGP)

decreased systemic arterial diastolic blood pressure (IAGP)

decreased systemic arterial systolic blood pressure (IAGP)

increased body weight (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

Options:

View chart

Download data table

View expanded data table

Clinical Measurement

heart rate

systolic blood pressure

diastolic blood pressure

mean arterial blood pressure

body weight

References

References - curated

#	Reference Title	Reference Citation
1.	Congenic strains provide evidence that four mapped loci in chromosomes 2, 4, and 16 influence hypertension in the SHR.	Aneas I, etal., Physiol Genomics. 2009 Mar 3;37(1):52-7. Epub 2009 Jan 6.
2.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D2Rat226)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	164,073,756 - 164,074,002 (+)	MAPPER
Rnor_6.0	2	177,680,772 - 177,681,017	NCBI
Rnor_5.0	2	197,020,226 - 197,020,471	UniSTS
RGSC_v3.4	2	170,338,294 - 170,338,540	RGD
RGSC_v3.4	2	170,338,295 - 170,338,540	UniSTS
RGSC_v3.1	2	170,288,281 - 170,288,707	RGD
Celera	2	158,172,109 - 158,172,348	UniSTS
SHRSP x BN Map	2	69.1098	RGD
SHRSP x BN Map	2	69.1098	UniSTS

Flank 2 / 1 (D2Rat294)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	227,146,480 - 227,146,641 (+)	MAPPER
Rnor_6.0	2	243,901,215 - 243,901,375	NCBI
Rnor_5.0	2	262,434,913 - 262,435,073	UniSTS
RGSC_v3.4	2	236,153,361 - 236,153,712	RGD
RGSC_v3.4	2	236,153,374 - 236,153,534	UniSTS
RGSC_v3.1	2	236,140,114 - 236,140,274	RGD
Celera	2	219,301,590 - 219,301,750	UniSTS
RH 3.4 Map	2	1606.1	UniSTS
RH 3.4 Map	2	1606.1	RGD
RH 2.0 Map	2	1176.8	RGD
SHRSP x BN Map	2	97.6098	RGD
FHH x ACI Map	2	110.7499	RGD

Strain QTL Data

Symbol	Name	Trait
Bp337	Blood pressure QTL 337	arterial blood pressure trait (VT:2000000)

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: SHR.BN-(D2Rat226-D2Rat294)/Jk

Mammalian Phenotype

Related Phenotype Data for Term "SHR.BN-(D2Rat226-D2Rat294)/Jk" (RS:0002155)