Strain Report - Rat Genome Database

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Strain: Kini:DA,PVG-G12

Symbol: Kini:DA,PVG-G12
Strain: Kini:DA,PVG-G12
RGD ID: 2306784
Citation ID: RRID:RGD_2306784
Ontology ID: RS:0002040
Also Known As: G12; G12
Type: advanced_intercross_line
Available Source: Not Available
Origination: Center for Molecular Medicine, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
Description: Two breeding pairs from inbred DA/Han and PVG/OlaHsd that share the RT1a MHC haplotype were bred to create F1 generation, 7 couples of F1 with DA/Han and PVG/OlaHsd females founders generated F2. F3 generation originated from breeding 50 random couples
Inbred Generations: G12
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome. Huberle A, etal., J Immunol. 2009 Apr 1;182(7):4432-8.
2. RGMA and IL21R show association with experimental inflammation and multiple sclerosis. Nohra R, etal., Genes Immun. 2010 Jun;11(4):279-93. Epub 2010 Jan 14.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Eae30 Experimental allergic encephalomyelitis QTL 30 nervous system integrity trait   (VT:0010566)    
Eae31 Experimental allergic encephalomyelitis QTL 31 nervous system integrity trait   (VT:0010566)    
Ean2 Experimental allergic neuritis QTL 2 nervous system integrity trait   (VT:0010566)    
Ean3 Experimental allergic neuritis QTL 3 nervous system integrity trait   (VT:0010566)    
Ean4 Experimental allergic neuritis QTL 4 nervous system integrity trait   (VT:0010566)    
Ean5 Experimental allergic neuritis QTL 5 nervous system integrity trait   (VT:0010566)    
Ean6 Experimental allergic neuritis QTL 6 nervous system integrity trait   (VT:0010566)    
Pia41 Pristane induced arthritis QTL 41 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems induced by bovine PNM 2306769
strain_life_disease disease was observed more in females 2306769