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Strain: SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr

Symbol: SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr
Strain: SHRSP.ZUC-(D5Rat4-D5Rat36)
Substrain: IzmDmcr
RGD ID: 2300018
Citation ID: RRID:RGD_2300018
Ontology ID: RS:0001635
Also Known As: SHRSP fatty; SHRSP.ZF; NBRP Rat No: 0447; SHRSP.Z-(D5Rat4-D5Rat36)/IzmDmcr;SHRSP fatty(fa/fa);SHRSP fatty(fa/fa);SHRSP.Z-Leprfa/IzmDmcr;; SHRSP.Z-Leprfa/IzmDmcr; SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: Mukogawa Women's University, Nishinomiya, Hyogo Japan
Description: Selective back cross breeding was done with SHRSP/Izm and Zucker fatty rats for 12 generations to introduce Lepr locus of chr 5 from Zucker fatty rats into SHRSP/Izm
Last Known Status: Live Animals
Research Usage Diabetes Obesity; Cardio Hypertension


References - curated
# Reference Title Reference Citation
1. Establishment of a new animal model of metabolic syndrome: SHRSP fatty (fa/fa) rats. Hiraoka-Yamamoto J, etal., Clin Exp Pharmacol Physiol. 2004 Jan-Feb;31(1-2):107-9.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines
4. Cardiovascular remodeling and metabolic abnormalities in SHRSP.Z-Lepr(fa)/IzmDmcr rats as a new model of metabolic syndrome. Ueno T, etal., Hypertens Res. 2008 May;31(5):1021-31.


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_reproduction Maintained by crossing heterozygotes of the fa/fa locus. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-18 SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr    SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr    Name updated 68913 APPROVED
2012-05-18 SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr    SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr    Name updated 68913 APPROVED