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Strain: Kini:DA,PVG-G10

Symbol: Kini:DA,PVG-G10
Strain: DA,PVG-G10
Substrain: Kini
RGD ID: 2298494
Citation ID: RRID:RGD_2298494
Ontology ID: RS:0001339
Type: advanced_intercross_line
Available Source: Not Available
Origination: Center for Molecular Medicine, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
Description: Two breeding pairs from inbred DA/Han and PVG.1AV1 that share the RT.1AV1 MHC haplotype were bred to create F1 generation, 7 couples of F1 with DA/Han and PVG.1AV1 females founders generated F2. F3 generation originated from breeding 50 random couples
Inbred Generations: G10
Last Known Status: Unknown

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype


References - curated
# Reference Title Reference Citation
1. New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Becanovic K, etal., J Immunol 2003 Jan 15;170(2):1062-9.
2. An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. Jagodic M, etal., J Immunol 2004 Jul 15;173(2):1366-73.
3. RGMA and IL21R show association with experimental inflammation and multiple sclerosis. Nohra R, etal., Genes Immun. 2010 Jun;11(4):279-93. Epub 2010 Jan 14.
4. Definition of a 1.06-Mb region linked to neuroinflammation in humans, rats and mice. Ockinger J, etal., Genetics. 2006 Jul;173(3):1539-45. Epub 2006 Apr 19.
5. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Strain QTL Data
Symbol Name Trait
Eae23 Experimental allergic encephalomyelitis QTL 23 nervous system integrity trait   (VT:0010566)    
Eae30 Experimental allergic encephalomyelitis QTL 30 nervous system integrity trait   (VT:0010566)    
Eae31 Experimental allergic encephalomyelitis QTL 31 nervous system integrity trait   (VT:0010566)    
Eae32 Experimental allergic encephalomyelitis QTL 32 nervous system integrity trait   (VT:0010566)    
Eae33 Experimental allergic encephalomyelitis QTL 33 nervous system integrity trait   (VT:0010566)    
Pia41 Pristane induced arthritis QTL 41 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease disease was observed more in females 2293859
strain_life_disease induced by myelin oligodendrocyte glycoprotein aa1-125 2293859