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Strain: ACI.COP-(D6Rat80-D6Rat146)/Shul

Symbol: ACI.COP-(D6Rat80-D6Rat146)/Shul
Strain: ACI.COP-(D6Rat80-D6Rat146)
Substrain: Shul
RGD ID: 2292564
Citation ID: RRID:RGD_2292564
Ontology ID: RS:0001161
Previously known as: ACI.COP-Ept1; ACI.COP-Ept1; Ept1; ACI.COP-(D6Rat80-D6Rat146)/Shul; ACI.COP-(D6Rat80-D6Rat146)/Shul
Type: congenic
Source: Department of Genetics, Cell Biology and Anatomy, University Of Nebraska Medical Center, Omaha, Nebraska
Origin: Female COP/CrCrl and male ACI/SegHsd were crossed to get F1 progeny which were in turn backcrossed with female ACI/SegHsd; the offsprings were genotyped
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.262,299,357 - 2,299,495RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0616,100,120 - 16,100,257RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0626,052,697 - 26,052,834RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4616,302,145 - 16,302,283RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Tissue-Specific Actions of the Ept1, Ept2, Ept6, and Ept9 Genetic Determinants of Responsiveness to Estrogens in the Female Rat. Kurz SG, etal., Endocrinology. 2008 Apr 17;.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D6Rat108)
Rat AssemblyChrPosition (strand)Source
mRatBN7.262,299,357 - 2,299,495 (-)MAPPER
Rnor_6.0616,100,120 - 16,100,257NCBI
Rnor_5.0626,052,697 - 26,052,834UniSTS
RGSC_v3.4616,302,145 - 16,302,283RGD
RGSC_v3.4616,302,146 - 16,302,283UniSTS
RGSC_v3.1616,303,143 - 16,303,281RGD
SHRSP x BN Map61.1899UniSTS
SHRSP x BN Map61.1899RGD
FHH x ACI Map61.26RGD

Flank 2 / 1 (D6Rat146)
Rat AssemblyChrPosition (strand)Source
RH 2.0 Map6180.1RGD
SHRSP x BN Map622.8698RGD
Strain QTL Data
Symbol Name Trait
Emca10 Estrogen-induced mammary cancer QTL 10 mammary gland integrity trait   (VT:0010552)    
Ept15 Estrogen-induced pituitary tumorigenesis QTL 15 pituitary gland mass   (VT:0010496)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other COP allele inhibited the induction of pituitary growth by E2 at 12 weeks but not observed at 28 weeks 2292503

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-11-07 ACI.COP-(D6Rat80-D6Rat146)/Shul    ACI.COP-(D6Rat80-D6Rat146)/Shul    Name updated 68913 APPROVED
2014-11-07 ACI.COP-(D6Rat80-D6Rat146)/Shul    ACI.COP-(D6Rat80-D6Rat146)/Shul    Name updated 68913 APPROVED