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Strain: SS-Tg(ApoC3-CETP)53Opaz

Symbol: SS-Tg(ApoC3-CETP)53Opaz
Strain: SS-Tg(ApoC3-CETP)53Opaz
RGD ID: 2290429
Citation ID: RRID:RRRC_00310
Ontology ID: RS:0001482
Also Known As: Tg[hCETP]DS; Tg[hCETP]DS; Tg[hCETP]53; Tg[hCETP]53
Type: transgenic
Available Source: Rat Resource and Research Center
Origination: Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Description: SS/JrHsd embryos were microinjected with 1.57 kb human CETP cDNA construct into pSV-SPORT1 with human ApoC3 promoter
Coat Color: white
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm





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Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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References

References - curated
# Reference Title Reference Citation
1. Genome-wide scan for interacting loci affecting human cholesteryl ester transfer protein-induced hypercholesterolemia in transgenic human cholesteryl ester transfer protein F2-intercross rats. Herrera VL, etal., J Hypertens. 2007 Aug;25(8):1608-12.
2. Spontaneous combined hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive hypertensive rats transgenic for human cholesteryl ester transfer protein. Herrera VL, etal., Nat Med. 1999 Dec;5(12):1383-9.
3. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Scl54 Serum cholesterol level QTL 54 blood cholesterol amount   (VT:0000180)    
Scl55 Serum cholesterol level QTL 55 blood cholesterol amount   (VT:0000180)    
Scl56 Serum cholesterol level QTL 56 blood cholesterol amount   (VT:0000180)    
Scl57 Serum cholesterol level QTL 57 blood cholesterol amount   (VT:0000180)    
Scl58 Serum cholesterol level QTL 58 blood cholesterol amount   (VT:0000180)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics males are hemizygous since transgene is on the X-chromosome. 2290427
strain_reproduction sib-mating 2290427

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-11-24 SS-Tg(ApoC3-CETP)53Opaz    SS-Tg(ApoC3-CETP)53Opaz    Name updated 68913 APPROVED
2014-11-24 SS-Tg(ApoC3-CETP)53Opaz    SS-Tg(ApoC3-CETP)53Opaz    Name updated 68913 APPROVED
2013-07-03 SS-Tg(ApoC3-CETP)53Opaz    SS-Tg(ApoC3-CETP)53Opaz    Name updated 68913 APPROVED
2013-07-03 SS-Tg(ApoC3-CETP)53Opaz    SS-Tg(ApoC3-CETP)53Opaz    Name updated 68913 APPROVED
2012-04-19 SS-Tg(ApoC3-CETP)53Opaz    SS-Tg(ApoC3-CETP)53Opaz    Name updated 68913 APPROVED
2012-04-19 SS-Tg(ApoC3-CETP)53Opaz    SS-Tg(ApoC3-CETP)53Opaz    Name updated 68913 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00310 RGD