Strain Report - Rat Genome Database

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Strain: F344.GK-(D1Rat175-D1Rat90)/Swe

Symbol: F344.GK-(D1Rat175-D1Rat90)/Swe
Strain: F344.GK-(D1Rat175-D1Rat90)
Substrain: Swe
RGD ID: 1600344
Citation ID: RRID:RGD_1600344
Ontology ID: RS:0001300
Previously known as: F344.GK-(D1Rat175-D1Rat90)/Swe; N1IREC6
Type: congenic
Source: Karolinska Institutet, Stockholm, Sweden
Origin: This is a congenic substrain derived by intercrossing female F344/Crl and male F344.GK-(D1Arb42a-D1Rat90)/Swe. F2 progeny carried the homozygous GK/Swe genome in different segments. These were then maintained by bxs breeding.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21259,647,732 - 259,647,894RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01281,795,624 - 281,795,785RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01289,137,107 - 289,137,268RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41267,110,921 - 267,111,153RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes. Granhall C, etal., Diabetes. 2006 Dec;55(12):3494-500.
2. High-resolution quantitative trait locus analysis reveals multiple diabetes susceptibility loci mapped to intervals<800 kb in the species-conserved Niddm1i of the GK rat. Granhall C, etal., Genetics. 2006 Nov;174(3):1565-72. Epub 2006 Sep 1.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Position Markers

Flank 1 / 1 (D1Rat175)
Rat AssemblyChrPosition (strand)Source
FHH x ACI Map1130.2499UniSTS
FHH x ACI Map1130.2499RGD

Flank 2 / 1 (D1Rat90)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21259,647,732 - 259,647,894 (+)MAPPER
Rnor_6.01281,795,624 - 281,795,785NCBI
Rnor_5.01289,137,107 - 289,137,268UniSTS
RGSC_v3.41267,110,926 - 267,111,087UniSTS
RGSC_v3.41267,110,921 - 267,111,153RGD
RGSC_v3.11267,322,011 - 267,322,172RGD
Celera1255,291,309 - 255,291,470UniSTS
RH 3.4 Map11708.8RGD
RH 3.4 Map11708.8UniSTS
RH 2.0 Map11313.1999RGD
SHRSP x BN Map1148.15RGD
Strain QTL Data
Symbol Name Trait
Niddm64 Non-insulin dependent diabetes mellitus QTL 64 blood glucose amount   (VT:0000188)    
Niddm66 Non-insulin dependent diabetes mellitus QTL 66 blood glucose amount   (VT:0000188)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other This has the entire region of Niddm35 QTL except 0.8Mb at the proximal end. 1599587

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-28 F344.GK-(D1Rat175-D1Rat90)/Swe    F344.GK-(D1Rat175-D1Rat90)/Swe    Name updated 68913 APPROVED
2013-08-28 F344.GK-(D1Rat175-D1Rat90)/Swe    F344.GK-(D1Rat175-D1Rat90)/Swe    Name updated 68913 APPROVED